What is Seliciclib?

Seliciclib (roscovitine or CYC202) is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors that preferentially inhibit multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase or state within the cell cycle of treated cells. Seliciclib is being developed by Cyclacel.

Seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), Cushing's Disease, leukemia, HIV infection, herpes simplex infection, cystic fibrosis and the mechanisms of chronic inflammation disorders.

Questions and answers on "Seliciclib"

Need to know what degree of side effects is of the drug --LEE011--- that I am about to get in my clinical trial? ---I have secondary progressive MS...

doctor1 MD


Till now the clinical trial for LEE011 shows that it has minor side effects only which you have mentioned here. This is why they are switching...

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