Rilpivirine

What is Rilpivirine?

Rilpivirine (TMC278, trade name Edurant) is a pharmaceutical drug, developed by Tibotec, for the treatment of HIV infection. It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.

Rilpivirine entered phase III clinical trials in April 2008, and was approved for use in the United States in May 2011. A fixed-dose drug combining rilpivirine with emtricitabine and tenofovir, was approved by the U.S. Food and Drug Administration in August 2011 under the brand name Complera; it was licensed in the European Union under the brand name Eviplera in November 2011.

Questions and answers on "Rilpivirine"

I got urticaria 7 1/2 weeks into Complera. My doctor told me to stop taking it immediately just 4 days short of my next refill because of concerns...

doctor1 MD

Hi,

Thanks for writing in.

Complera is emtricitabine / rilpivirine / tenofovir in oral tablet. This is an effective and well tolerated combination...

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Recently involved in a car wreck that left me with a sprained tibia. General Family Practice doctor prescribed me "Diclofenac" to help with the pain...

doctor1 MD

Hello

Thanks for the query

There are no known interactions between these two drugs however I would advice you to take a safer profile analgesic...

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Recent questions on  Rilpivirine

doctor1 MD

Recently involved in a car wreck that left me with a sprained tibia. General Family Practice doctor prescribed me "Diclofenac" to help with the pain...

doctor1 MD

I got urticaria 7 1/2 weeks into Complera . My doctor told me to stop taking it immediately just 4 days short of my next refill because of concerns...

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