What is Rifabutin?

Rifabutin (Rfb) is a bactericidal antibiotic drug primarily used in the treatment of tuberculosis. The drug is a semi-synthetic derivative of rifamycin S. Its effect is based on blocking the DNA-dependent RNA-polymerase of the bacteria. It is effective against Gram-positive and some Gram-negative bacteria, but also against the highly resistant Mycobacteria, e.g. Mycobacterium tuberculosis, M. leprae, and M. avium intracellulare.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Questions and answers on "Rifabutin"

I have microm bateria avion complex. Found this out about 5 years ago.I have been using azithromycin to help with the lung infection. It seems to...

doctor1 MD

Brief Answer:
Moxifloxacin and Rifabutin can be superior alternatives.

Detailed Answer:
Hello Sir.

New drugs particularly Moxifloxacin and...

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Hi,I currently take the combined contraceptive pill, microgynon 30 however i have recently been prescribed the antibiotic erythromycin. I have...

doctor1 MD


Birth control pills work best when taken on the regular basis, in the right time time everyday. The efficacy may get affected if the doses...

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I was diagnoised with MYCOBACTERIUM in both lungs. The doctor prescribed CLARITHROMYCIN 500MG TAB. He said this was the ONLY medication that would...

doctor1 MD

By saying Mycobacterium, I suppose you are referring to Atypical Mycobacteria, or Non tubercular mycobacteria, because only this Mycobacterium is...

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