Prothiaden

What is Prothiaden?

Dosulepin (INN, BAN) formerly known as dothiepin (USAN), and marketed under the brand names Prothiaden, Dothep, Thaden, and Dopress, is a tricyclic antidepressant that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not used in the United States.

Questions and answers on "Prothiaden"

atarax 25 and prothiaden 25 mg can taken together

doctor1 MD

Brief Answer:
Yes they can be taken together; mild drug interaction might be present

Detailed Answer:
Hi,
Thank you for posting your query in Healthcaremagic.com.
This is Dr. Swarnava Dattagupta answering your query.

I understand your concern.
Atarax contains hydroxyzine which is used as...

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sir i am 40 year male and i took prothiaden 75mg a year later tapered to 50 mg that was continued for a year and then right now I am on 25mg for 2 years. Sir mental health is very much improved and i am planning to have a baby now.

My question is whether there will be any possible or adverse reaction that will affect the unborn baby in future as I am on medication for long time?

doctor1 MD

Brief Answer:
It has no harmful effect on the growing fetus (unborn child)

Detailed Answer:
Hi & Welcome.
I can understand your concern regarding the safety of Prothiaden.

Prothiaden (Dothiepin) is a tricyclic antidepressant used to treat depression & it also helps to reduce the feelings of...

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Hi am I am 39 years old female. Last two years I have been on Aten 25 mg once a day. Prothiaden 50 mg once a day for last 3 years for migraine. I have lonazep sos for anxiety.

I see fluctuations in bp that are very high particularly when im emotionally disturbed or overthinking something. Eg today I woke up from an afternoon nap with a 129/107. Within minutes the second reading was 96/68 and the third was 121/65. I also have recently been diagnosed with thick endometrial lining , possible polyp, which needs a d&c. Not sure about whats going on inside me!


Hi,

My question got submitted before completion.

Have Aten 25 mg once a day last 2 years for bp
Prothiaden 50 mg once a day for migraine
Lonazep sos for Anxiety.

Had PCOD 15 yrs ago which was cured.
Had hypothyroidism which got overcorected so discontinued medication about 4 yrs ago.

Got a full body health chk done recently and have the following:

Fibroglandular parenchyma for both breasts- Mammogram-BIRADS1


USG whole Abdomen with TVS shows:
Thickened endometrium with a small focal echogenic vascular area- poly
Suggested to have a Hysteroscopy, polypectomy and D/C

My mother was recently daignosed with stage 2 ductile carcinoma. And fathers immediate sister had it, so there is a high probability of cancer im told.

A lot of issues there but my main worry is about the Fluctuation in BP. Is such a heavy variation normal . One day it was 179/117 and next morning was 103/77. Are all these linked to hormonal issues. I must add that I have been under extreme emtional stress last 14-15 years and feel there could be a connection somewhere. Are there in further tests I need for the hormones ?

doctor1 MD

Brief Answer:
Yes all three of your problems could be hormone related and get exacerbated

Detailed Answer:
Hi XXXXXXX welcome to HCM,

Yes all three of your problems could be hormone related and get exacerbated by stress.

Regarding your Blood pressure, yes it can fluctuate like this in many...

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hello Doctor ... am suffering from anxiety and fear if travel .. symptoms are of Agoraphobia ... also i have lots of anxiety when am travelling from one place to another especially via airplanes and i am in constant fear of having a panic attack ..
could you please suggest some medication/therapy/remedy for the same as am bound to travel a lot due to my job

i used take take paxidep cr 0.5 earlier and my problem was resolved to quiet an extent ..however i discontinued the medicine due to weight gain and sexual dysfunction .. so could you suggest an alternative medicine please

doctor1 MD

Brief Answer:
Psychotherapy and behaviour therapy work in anxiety disorder

Detailed Answer:
Hello,

Thanks for writing to us.

I can understand your concern for anxiety.

From history and treatment it seems that you are likely suffering from Panic disorder with agoraphobia.

Pexidep CR 12.5(not 0.5)...

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Hello Dr Narsi. I am 68 male. Pacemaker replaced in Apr 14. Hypertension past 30 yrs. Taking CTD 12.5, Telmasartan 80 + Amlodepine 5 daily. Have BPH. Am Hep B past 10yrs post angiography. LFT normal. Having headaches past 21/2 yrs. CT scan showed - prominent vessel in left frontal lobe suggesting underlying incidental venous angioma. There is prominent perivascular space in left basal ganglia & mild cerebal atrophy changes. Am on 25 mg Protheiden since 06th April 14. Still get them but not so severe. Having severe burping/belching past 6 months. Feel lightheaded too. Acidity problems are there past number of years. Took Pantop-D and Itopride for 2 months (doctors advise). Ultrasound of abdomen all good except for BPH and some post void retention. Felt much better but is back again . Motions regular & normal. No stomach pain as such. Any dietery related? Am veg. Stopped wheat. Please advise.

doctor1 MD

Brief Answer:
Dyspepsia

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.
It seems that you are having dyspepsia most likely NUD (non ulcer dyspepsia ). Irritable bowel syndrome often co-exist.Unspecified excessive belching is a sub classifiication(B2) under...

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i am 37 male.. and diagnosed two tyms with hyponondriasis( anticipatory health anxiety) by a psychiartist and under gone treatment wt veniz xr 75 mg.. got good remission also.. last tym 3 yr bfore my anxiety again returned in the form of a fear towards the onset psychosis ...sply schizophrenia... (early tyms it was hiv infection frmn open space.).
and my psychairtist changed the drig yo prothiaden (dosulepin) 150mg wt topicalm (tofisapam) 100mg two times daily.. this change due to get good sleep tht he told..
bt.. in tht tym aftr four week he stoppd topicalm, on the next moment my anxiety terribly shoot up .. and change its nature from hypocondriasis to primarly obsession.. ( fearing to be accidently engaged in crime , chance to have change in sexual preference... such).. i really fed up...it was chronic.. then i visitd my psychiartst and he reduced prothiaden 150 to 75.. and add new medcine flouxetine 20mg.. .. bt no improvemnt... next visit he upgrade flouxetine to 60mg and reduced prothiaden from 75 to 50.. aftr two weeks i cud feel better... and my obsessional thoughts reduced its intensity.. and remitted 50℅.. anixiety also reduced... then the next visit dr upgraded flouxetine to 80 mg daily and reduced prothiaden to 25 mg.. nw i am going this treatment and i got 60℅ remission in my obsessional thoughts and anxiety... sir my parents are doctors .. general physician.. and they are clearin my doubts... bt in tht crucial anxiety shooted level , onwards i cudnt accept my parents completely... and i have reqmain a question on mind tht.. what if .. if it happend... ..
my anxiety has changed its nature aftr tht... then onwards i cud loss my rational thinking and accepting ability. bt nw a days it slowly return.. i can understand almost things... and in the tym of severe level anxiety, my parents assured tht i never be a psychotic level and all tym i keep and controll my anxiety from others and society.. i am sure,tht even in the chronic level i didnt lost the reality, only happend some confusion state...

my long essay may be borin u.. bt help me for gettin relief... these are my history... here i need to knw some details cz a psychiartist assurance wll accept by mind completely...

sir

really my problem is hypocondriasis or ocd?
is it ocd , it can be controllable means can i get bettr...
and hv any chance to lead this obsession to delusion or schizophrenia..
in this age have any chance for devlopn schizo... cz i read some article tht scizho is men aftr age 35..
sir
my skin is senstive and sme times its itchy... and that itchnes feels discomfrt me... and when itch nesa feela ,i feard tht it may leads to deluaional parasitosis ideas by my mind,cz i am fearin my mind can think any level...
sir this fear of delusional para may leads to real delusional disorders?..

i knw its a long essay.. sorry for that.. i am 35 male...with good health..no famly history of psychosis and severe mental disorder.. no childhood trauma... parents are doctors.. and father has also a little bit anxious bt in controllable level... thanku sir


doctor1 MD

Brief Answer:
it is ocd-anxiety, possibility of schizophrenia is nill

Detailed Answer:
Hello Sreejith,

Thanks for writing to us. I can understand your concern.

You have very well narrated your history. It is clear that you have anxiety problem only, not psychotic. You had obsessional thoughts...

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Doctor have adviced medicine like feliz-s-10 (for 6 month) gradually with 1/2 tablet, 1 tablet and 2 tablet a day, prothiaden (for 6 month) gradually with 25 mg, 50 mg and 75 mg and clobakem-10 (for 1 month) for patient who has developed nurvousness, worriedness, sleepless , weakness etc due to family member health issue since last 2-3 months. Before this the patient was quite healthy and strong mentally . I want to know that is there any chance of developing new health complition in future due to side effect of taking these medicine . Is there any chance of addiction and above health problem be repeated when discontinued.

doctor1 MD

Brief Answer:
avoid prothiaden, not good for heart patients

Detailed Answer:
Hello,
The meds are fine except that we prefer to treat patient with one drug and not three for same complaint.
Secondly, prothiaden is not given in any patient who has any kind of cardiac history including...

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I am 39 yr lady with chronic stress systems for last 14-15 years. Had pcod, had hyperthyroidism that got over corrected after 2 yrs and i discontinued electroxin. Then started having migraines and was put on prothiaden 50 mg . Also had intermittent High bp. Am on prothiaden 50 mg at bedtime and Aten 25 for bp in the morning last 3 yrs. nov 2016 had thicked uterus lining for which i had a dnc done. Again hormonal imbalance was the likely cause. My period cycles are regular last 3 times post dnc. However the bp fluctuates drastically.

Had an ambulator put for 24 hrs . Results are as follows:

Avg daytime 138.3/85.4
Avg nighttime 100/22.2
Diff in day/ night avg. -17.1/-22.6

Sys bp min 101, XXXXXXX 252!!
Dia bp min 53 XXXXXXX 196!!
Heart rate 50 XXXXXXX 98

These readings look alarming to me.

Also got an mri brain done 3 yrs ago and it said acute is hemiec foci on the left side. Im wondering if this has a connevtion.

All night readings are very low , while the day readings are alarmingly high.

Can u pls advice if i am sustebile to a stroke and what really is happening

doctor1 MD

Brief Answer:
Blood pressure is normally lower at night. This is called nocturnal dipping

Detailed Answer:
Hi XXXXXXX welcome back. I reviewed you previously.
Blood pressure is normally lower at night. This is called nocturnal dipping. Yes your fluctuations are more.
I will suggest you switch to...

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I have been suffering from depression and anxiety problem since last year and have been Nexito LS and Necito Forte and Mirtaz 15mg initial for 2 months. After advised 3 months - Nexito 10mg(1-0-0) & Prothiaden 75mg(0-0-1) After 3 months till 6 months - Nexito 10mg(1-0-0) & Prothiaden 50mg(0-0-1) After 6 months till 9 months - Nexito 10mg(1-0-0) & Prothiaden 25mg(0-0-1) Is this the right dose to come off the drugs? My physician is not available for immediate discussio

doctor1 MD

hello

welcome to health care magic

Nexito contains escitalopram 10 mg which is an efficacious antidepressant (SSRI) with minor side effects. Prothiaden is a TCA which is again an antidepressant. You have been prescribed adequate dosages. So no need to be worried. Continue the medication for...

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good afternoon doctor - I have been put on bupron xl 300 along with other medication as under:
quetiapine 150, tynept 12.5, Librium 10, lurasid 60 all in the night
tynept 37.5 od, bupron xl 300, Librium 10 in the morning
my fear of meetings and meeting strangers is still there, thought bupron would help me but it has not helped me significantly. after 10 days of taking bupron I am feeling burning sensation (pins and needles like sensation ) on the tongue and getting a slight pain on the side and the top of the tongue while swallowing. spoke to my doctor and he has told me to take neurobion forte in the morning but that does not seem to be helping me. does bupron cause such side effect? it is quite bothersome for me and am in a dilemma as to what to do? what would your advise be?

doctor1 MD

Brief Answer:
If tongue sensations persist then divide the doses to 150 mg twice a day

Detailed Answer:
Hello again,

The drug will supplement the actions of the drugs you're taking but please give the medicines time to show effects. Avoid anticipating the things, keep your hopes alive....

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Recent questions on  Prothiaden

doctor1 MD

good afternoon doctor - I have been put on bupron xl 300 along with other medication as under: quetiapine 150, tynept 12.5, Librium 10, lurasid 60 all in the night tynept 37.5 od, bupron xl 300, Librium 10 in the morning my fear of meetings and...

doctor1 MD

I am 39 yr lady with chronic stress systems for last 14-15 years. Had pcod, had hyperthyroidism that got over corrected after 2 yrs and i discontinued electroxin. Then started having migraines and was put on prothiaden 50 mg . Also had...

doctor1 MD

Hi am I am 39 years old female. Last two years I have been on Aten 25 mg once a day. Prothiaden 50 mg once a day for last 3 years for migraine . I have lonazep sos for anxiety. I see fluctuations in bp that are very high particularly when im...

doctor1 MD

I was on prothiaden due to GERD (with anxiety) 100 mg for 1 month along with Domperidone 20 mg ,2 month 50 mg prothiaden,1 month 25 mg prothiaden, 12.5 mg prothiaden for another 1 month, now I am taking 12.5 mg prothiaden alternate days....I am feeling balance problem and headache something.....Are these due to withdrawal and when will it will disappear ?

doctor1 MD

I have been suffering from depression and anxiety problem since last year and have been Nexito LS and Necito Forte and Mirtaz 15mg initial for 2 months. After advised 3 months - Nexito 10mg(1-0-0) & Prothiaden 75mg(0-0-1) After 3 months till 6 months - Nexito 10mg(1-0-0) & Prothiaden 50mg(0-0-1) After 6 months till 9 months - Nexito 10mg(1-0-0) & Prothiaden 25mg(0-0-1) Is this the right dose to come off the drugs? My physician is not available for immediate discussio

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