What is Prograf?

Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, 'Protopic) is an immunosuppressive drug used mainly after allogeneic organ transplant to reduce the activity of the patient's immune system and to lower the risk of organ rejection. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo.

It is a 23-membered macrolide lactone discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukubaensis. It reduces interleukin-2 (IL-2) production by T-cells.

Questions and answers on "Prograf"

I am taking Prograf 7 mg bid as I had a liver transplant on July 21/13. I was searching side effects of prograf and notice alopecia is one of them....

doctor1 MD

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Prograf is a brand name of immunosuppressant drug...

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hi my kindey transplant done in feb 2012 now after 1 year creatine levele is 1.5 ..pls suggest is it goor or not?
prograf :2 mg
cellceft:360 mg in...

doctor1 MD

HI, thanks for using healthcare magic

The normal upper limit for creatinine is usually quoted as 1.2, though there may be some variation from lab...

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