What is Profen?

Ibuprofen ( or ; from isobutylphenylpropanoic acid) is a nonsteroidal anti-inflammatory drug (NSAID) derivative of propionic acid used for relieving pain, helping with fever and reducing inflammation. About 60% of people improve with any given NSAID and it is recommended that if one does not work that another should be tried.

Compared to other NSAIDs it may have fewer side effects such as gastrointestinal bleeding. At low doses it does not appear to increase the risk of myocardial infarction; however, at higher doses it may. It may result in worsened asthma.

Like other NSAIDs, it works by inhibiting the synthesis of prostaglandins, which are fat-like molecules derived from arachidonic acid, which are involved in mediating inflammation (swelling), pain, and fever. It achieves this effect on prostaglandin synthesis by inhibiting cyclooxygenase, an enzyme that is present in various tissues of the body.

It was originally made and patented in 1961, by the research arm of Boots Company led by Stewart Adams and marketed as Brufen. Ibuprofen is now available under a variety of trade names, with the most notable being Advil, Motrin, and Nurofen. It was later marketed, in 1966, as a prescription drug in the United Kingdom, then the United States in 1974. Later in 1983 and 1984, it became the first NSAID (other than aspirin) to be available over the counter (OTC) in these two countries. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

Questions and answers on "Profen"

hi dear Dr , nice to meet u , i have sevear migren , and use depakine 500mg chrono a half morning and half night , im sportwoman , most of the time...

doctor1 MD

Hello dear,
I can understand your professional concerns are genuine regarding your weight gain.You are being given sodium valproate(depakine) 250...

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Will I pass out or die if I take more than 20 pills (200mg each) of IB profen?
If I dont die from this what are the possible effects that it will...

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Hi, I have been experiencing over the last 3 days Chills, a elevated temp, with aches and pains, and bad smelling farts that to this point seem to...

doctor1 MD

Thanks for your query.
Noted the history of suffering from chills, elevated temperature, aches and pains, bad smelling farts for the last 3...

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