Pregnenolone

What is Pregnenolone?

Pregnenolone (3β-hydroxypregn-5-en-20-one), also known as P5, is an endogenous steroid hormone. It is the precursor of the progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.

Questions and answers on "Pregnenolone"

I have a severe case of Restless Leg/Willis-Ekbom disease (RLS/WED). I have been on a variety of medications for it since 1990, most having lost...

doctor1 MD

Brief Answer:
Pregnenolone inhinits GABA-A

Detailed Answer:
Hi
Thanks for your query. I am Dr Vaishalee, MD (Pharmacology) and I will try to answer...

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Hello, I am 55 years old and my testicles have shrunken substantially and become soft with the associated problems you would expect. This occurred...

doctor1 MD

Brief Answer:
testicular health depends on testosterone, not HCG

Detailed Answer:
Hi there, thanks for coming to HealthCareMagic.

The first thing I...

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My blood work showed low pregnenolone of less than 10mg. I had a oophorectomy 2 years ago and surgery for hormone negative breast cancer. My...

doctor1 MD

Brief Answer:
Yes, low dose may be safe.

Detailed Answer:
Hi,

Thanks for writing to us about it.

I can see your concern here.

First and foremost...

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Recent questions on  Pregnenolone

doctor1 MD

I m a 50 yr old 160 lb triathlete. Take lots of supplements incl 50 mg DHA & 100 pregnenolone. Still have low normal test. Been on 3 pumps (37.5 mg...

doctor1 MD

I had a complete hysterectomy 14 years ago at age 25. I have not been able to find balance. I now have low thyroid function and low morning...

doctor1 MD

I have had C-scans and MRIs they come back negative. Not every night but most nights just before falling asleep I have head tremors or spasms, or...

doctor1 MD

I'm on adrenal meds, COq10, pregnenolone , DHEA and still feel exhausted. I still live my normal life, but it's an effort. I also have pain in my...

doctor1 MD

Hello, I am 55 years old and my testicles have shrunken substantially and become soft with the associated problems you would expect. This occurred...

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