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Podophyllin

What is Podophyllin?

Podophyllin is a resinous powder obtained by precipitating an alcoholic tincture of the rhizome of American Mayapple (Podophyllum peltatum) or Podophyllum emodi by means of water acidified with hydrochloric acid. It varies in color from grayish to bright yellow or greenish-brown, the first-named being the purest. It was once commonly used against HPV-induced genital warts because it contains antiwart lignans. Podofilox, a purified form of the main active ingredient, is currently recommended instead due to its higher efficacy and safety.

The powder is soluble in alcohol and strong solutions of alkalis, such as ammonia. Its composition is somewhat complex. There are certainly at least two resins in the powder (which is known officially as Podophylli resina), one of them being soluble and the other insoluble in ether. Each of these contains an active substance, which can be obtained in crystalline form, and is known as podophyllotoxin. It is soluble in alcohol, ether, chloroform and boiling water.

Questions and answers on "Podophyllin"

Hello I have genetal warts and doctor adivced me to be using calamine lotion I don't know if is right
Brief Answer:
Treatment options for genital warts

Detailed Answer:
Hello. Thank you for writing to us

I am dr.kakkar(dermatologist and venereologist). I have gone through your query and I have noted your concern.

Genital warts is an infection caused by Human Papilloma Virus (HPV). Calamine is...
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when Imiquad start to give results on genital warts.i am using it for a week and no result has come yet,even i feel it is getting bit bigger than earlier.
Brief Answer:
Regarding imiquimod for genital warts

Detailed Answer:
Helllo. Thank you for writing to us

I am dr.kakkar (dermatologist and venereologist). I have noted your concern.

Imiquimod 5% cream may take 2-4 weeks before it starts to show visible improvement. However, not all genital warts...
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I have different sized flat bumps on the side of my penis head. They do not itch, burn, or hurt whatsoever. I have researched online to see if it was genetal herpes but my condition does not seen to match the photos I cross-referenced online. When they first appeared 2 and a half months ago, I went in for an STI / HIV screening and was deemed negative for HIV, Gonorrhea, Clamydia, and Syphilis. I am attaching photographs of my condition in efforts to try to figure out what it is and see how I can correct it. Thank you.
Brief Answer:
Genital warts; Podophyllin resin, imiquimod Or CO 2 Laser

Detailed Answer:
Hello. Thank you for writing to us

I have gone through your query and I have also reviewed the images.

I can see skin colored raised bumps on glans penis.
These are genital warts. Genital warts are a viral...
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Dear doc since last few weeks I feel I hve anal warts near my anus. Not exactly the anus but at the top of it. Kindly pls prescribe some medicine. Also I get itch near the anal area.
Brief Answer:
Podophyllin

Detailed Answer:
Hello
Anal warts can be treated with podophyllin application however it needs to be applied by a trained person as it can cause burning.
Itch might be due to fungal infection.
Apply ointment clotrimazole twice daily for two weeks.
It is safe and...
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I have noticed two new “spots” on my penis, and I’m concerned this may be some kind of STD.

I’ve attached pictures. Spot 1 is whitish and hard. Spot 2 is smaller and soft. Spot 1 appeared 5th April . Second spot appeared 15th April. They are not itching or painful. They haven’t changed much since they appeared (writing this April 28th).

On 22 March I received oral sex from “girl 1”. On March 29 had unprotected vaginal sex with a girl who has a HPV strain (but no visible “spots”). Is it likely that I got anything from the oral sex?

I understand it’s hard to say, but are these blisters more likely to be HPV or herpes? Or something else?

Please send me a list of the lab tests I need to rule out all possible STDs including HSV1, HSV2, chlamydia, gonnorhea and anything else you would recommend?
Brief Answer:
possible genital warts

Detailed Answer:
Hello. Thank you for writing to us

I am dr.kakkar(dermatologist). I have gone through your query and i have noted your concern.
The images suggest that these could be warts i.e hpv infection. They dont seem like genital herpes.

Unprotected...
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Hi , what is condyloma acuminata ? And what are the side effects ? Dr gave me some drugs , how can i get rid of this ? Regards
Brief Answer:
Genital warts

Detailed Answer:
Hello and welcome to healthcaremagic.

Condyloma acuminata are genital warts. Genital warts clinically present as soft, fleshy, cauliflower like growths/papules, skin colored to pinkish in color on or around the genital mucosa. They are usually acquired...
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I developed a genital mole on 2005 and because it was itching I scratched it and it came off with lots of bleeding. After that the mole disappeared but a year later another one showed which I was afraid to scratch it and it has been there since then (8 years, see attached photo).
So I went to a dermatologist 6 years ago and she told me it was nothing that I should not worry but today while reading some articles about genital diseases I found that it could be a "genital wart" which I understand is a Human Papillomavirus (HPV) infection.

Can you please advise what I might have?. The mole itches sometimes, but not all the time and it has not bother me but now I am worried about it.
Are there any creams or treatments I can use to get rid off it?.

I have "fatty liver" so I would not like to take any medication that will affect my liver.

Thank you very much.
Brief Answer:
It look like a wart. The rough surface is suggestive!

Detailed Answer:
Hi and thank you so much for this query.

I am so sorry to hear about this lesion that you have reported. I have taken a look and it is very suggestive of a wart from its features. The best way is to scrape it...
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Ive hade some brown spots on penis for bout a year then they started to rais to some flat skin like done had for bout two years not growing
I wont get overly worried if the skin lesion is not growing,there is no itching in the lesion and there is no urinary problem.Skin lesions are better diagnosed by direct clinical examination.Would it be any infection it must have grown in such a long duration.
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Hi, I think I have an STD, but none of my research has helped. I have these wart like bumps. They are very small and at first I thought they were pimples. They are sometimes itchy, but not all the time. There is no pain whatsoever, but they do bleed occasionally. It seems to be getting worse. Please help. Thanks, XXXX
Brief Answer:
STD

Detailed Answer:
Hello,
Welcome to healthcare magic,
Thanks for uploading photographs. Your doubt seems to be correct. It is an STD. What you are having is called Genital warts caused by Human papilloma virus.

Please rule out other sexually transmitted infections like HIV,...
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Bump on pubic area , what is it and can it be removed ??
Brief Answer:
Wart

Detailed Answer:
Hello.

I am dr kakkar.

Its a wart. It is an infection caused by HPV.
It can be removed with electricautery.

Regards
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