Pentazocine

What is Pentazocine?

Pentazocine is a synthetically-prepared prototypical mixed agonist–antagonist narcotic (opioid analgesic) drug of the benzomorphan class of opioids used to treat moderate to moderately severe pain. Pentazocine is sold under several brand names, such as Fortral, Sosegon, Talwin NX (with the μ-antagonist naloxone, will cause withdrawal in opioid dependent persons on injection), Talwin, Talwin PX (without naloxone), Fortwin (Lactate injectable form) and Talacen (with acetaminophen). This compound may exist as one of two enantiomers, named (+)-pentazocine and (−)-pentazocine. (−)-pentazocine is a κ-opioid receptor agonist, while (+)-pentazocine is not, instead displaying a ten-fold greater affinity for the σ receptor. Usually, in its oral formulations, it is combined with naloxone so as to prevent people from crushing the tablets, dissolving them in a solvent (like water) and injecting them for a high (as naloxone is not orally bioavailable it produces no effect when the formulation is used orally, but it blocks the opioid effects of pentazocine if injected intravenously for a high). Related drugs include phenazocine, dezocine, cyclazocine and several chemicals used in research on the central nervous system.

Questions and answers on "Pentazocine"

What medicines I can not take for pain in my tooth?

doctor1 MD

Brief Answer:
avoid opioids....

Detailed Answer:
Hello,
Thanks for the query,
you can take NSAIDS like diclofenac sodium , aceclofenac, naproxen,...

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I am currently in Jamaica. Went scuba diving for the first time after having lessons. Today was first time out in the ocean. I ended up blowing my...

doctor1 MD

Brief Answer:
Get suction clearance of the ear under a microscope.

Detailed Answer:
Hi,

Thank you for your query.

1. Sea water entering the ear...

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Drug interaction of Talwin ns between other drugs?

doctor1 MD

Brief Answer:
risk of increased sedation.

Detailed Answer:
Hello
Welcome to HCM.

The major drug interaction between the drugs you have listed is...

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Recent questions on  Pentazocine

doctor1 MD

Hi I have had a renal transplant 3 years ago and would like to take s-adenosylmethione I am on other medication. I would like to have a...

doctor1 MD

I was recently diagnosed with hyperplasia (have a follow up app. next week. I have a dull pain in my vaginal area that does not go away (dull and...

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Drug interaction of Talwin ns between other drugs?

doctor1 MD

I ve been taking generic talwin nx for endometriosis pain. I have never heard of this drug until it was prescribed to me. I read somewhere that it...

doctor1 MD

Dear Dr, My nephew has been addicted to pentazocine for the past 4 years. He has been injecting himself with it and the tissues on his upper thighs...

doctor1 MD

Hi, Dr. I am addicted to taking pentazocine injection for my pain and it works well but lately I discovered that I am addicted to this drugs. How...

doctor1 MD

Hi. I live in Virgina Beach and have a 28y/o spinal disease and have gone through 15years of therapy. I don t do well on hard narcotics and I m...

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