What is Nefopam?

Nefopam (brand names: Acupan, Silentan, Nefadol and Ajan) is a centrally-acting but non-opioid analgesic drug of the benzoxazocine chemical class which was developed by Riker Laboratories in the 1960s. It is widely used, mainly in European countries, for the relief of moderate to severe pain as an alternative to opioid analgesic drugs. Animal studies have shown that nefopam has a potentiating (analgesic-sparing) effect on morphine and other opioids by broadening the antinociceptive action of the opioid and possibly other mechanisms, generally lowering the dose requirements of both when they are used concomitantly.

Questions and answers on "Nefopam"

Hi there...I am a midwife researching the use of Acupan (nefopam) for postnatal analgesia. I need to find out what FDA category it is. Also if...

doctor1 MD

Brief Answer:
Tramadol is a better alternative.

Detailed Answer:
Nefopam Hydrochloride belongs to FDA category D or X and is not recommended for...

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I have chronic hiccups. They are getting worse. At times I can't catch my breath and have to force myself to cough to get my breath back. Have...

doctor1 MD


Thank you for your query.

I am sure that your doctors have ruled out all the different causes of hiccups including problems with heart, lung...

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I am a 22 year old female who does a manual job and is usually fit and healthy. I ve suffered with abdominal pain for 6 months, beginning with...

doctor1 MD

Take full course of antiamebic
Take antacid sos

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