What is Motrin?

Ibuprofen ( or ; from isobutylphenylpropanoic acid) is a nonsteroidal anti-inflammatory drug (NSAID) derivative of propionic acid used for relieving pain, helping with fever and reducing inflammation. About 60% of people improve with any given NSAID and it is recommended that if one does not work that another should be tried.

Compared to other NSAIDs it may have fewer side effects such as gastrointestinal bleeding. At low doses it does not appear to increase the risk of myocardial infarction; however, at higher doses it may. It may result in worsened asthma.

Like other NSAIDs, it works by inhibiting the synthesis of prostaglandins, which are fat-like molecules derived from arachidonic acid, which are involved in mediating inflammation (swelling), pain, and fever. It achieves this effect on prostaglandin synthesis by inhibiting cyclooxygenase, an enzyme that is present in various tissues of the body.

It was originally made and patented in 1961, by the research arm of Boots Company led by Stewart Adams and marketed as Brufen. Ibuprofen is now available under a variety of trade names, with the most notable being Advil, Motrin, and Nurofen. It was later marketed, in 1966, as a prescription drug in the United Kingdom, then the United States in 1974. Later in 1983 and 1984, it became the first NSAID (other than aspirin) to be available over the counter (OTC) in these two countries. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

Questions and answers on "Motrin"

My 13 year old has been having stomach pain that has been gradually getting worse for a couple of days now. Been giving her motrin for pain and...

doctor1 MD

do a sonography of the abdomen to look for any anomalies
till then tab pantocid and domperidone 2 times daily 30 min b4 meals will help

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WITHOUT using medication. Is there any home remedies or something to relieve cramps? or do I have to take pills, I usually take motrin ib but I ran...

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