What is Motrin?

Ibuprofen ( or ; from isobutylphenylpropanoic acid) is a nonsteroidal anti-inflammatory drug (NSAID) derivative of propionic acid used for relieving pain, helping with fever and reducing inflammation. About 60% of people improve with any given NSAID and it is recommended that if one does not work that another should be tried.

Compared to other NSAIDs it may have fewer side effects such as gastrointestinal bleeding. At low doses it does not appear to increase the risk of myocardial infarction; however, at higher doses it may. It may result in worsened asthma.

Like other NSAIDs, it works by inhibiting the synthesis of prostaglandins, which are fat-like molecules derived from arachidonic acid, which are involved in mediating inflammation (swelling), pain, and fever. It achieves this effect on prostaglandin synthesis by inhibiting cyclooxygenase, an enzyme that is present in various tissues of the body.

It was originally made and patented in 1961, by the research arm of Boots Company led by Stewart Adams and marketed as Brufen. Ibuprofen is now available under a variety of trade names, with the most notable being Advil, Motrin, and Nurofen. It was later marketed, in 1966, as a prescription drug in the United Kingdom, then the United States in 1974. Later in 1983 and 1984, it became the first NSAID (other than aspirin) to be available over the counter (OTC) in these two countries. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

Questions and answers on "Motrin"

My 13 year old has been having stomach pain that has been gradually getting worse for a couple of days now. Been giving her motrin for pain and...

doctor1 MD

do a sonography of the abdomen to look for any anomalies
till then tab pantocid and domperidone 2 times daily 30 min b4 meals will help

Read Full Thread   Ask a Doctor Now

WITHOUT using medication. Is there any home remedies or something to relieve cramps? or do I have to take pills, I usually take motrin ib but I ran...

For an immediate answer, try our premium service   Ask a Doctor Now

Recent questions on  Motrin

doctor1 MD

I am a 25 year old male with intense testicular pain. It started 2 years ago with a gradual onset of non-specific right side testicular pain. I...

doctor1 MD

My son has had between a 102 and 103 fever for three days. Now I noticed he has a very red eye. He is 8. Can this be from the fever or is the fever...

doctor1 MD

My 2yr old daughter who is 34 lbs and 40 inches has had a on and off again fever for 48 hours which I have been treating with Tylenol and Motrin,...

doctor1 MD

My son has a high fever ranging between 101 - 105 degrees. His gums started swelling yesterday and he has a blister on his tongue. I have been...

doctor1 MD

I fell down stairs on my butt cheek, and now I have a hard and somewhat tender lump in that area. I had a huge bruise , but that is gone now, this...

doctor1 MD

I have pain in my back.If I do cycling exercise by lying down,in my right side it makes noise whereas it does not on my left side.Whenever I do...

doctor1 MD

hello doc i am having severe back pain from today morning i could not go for jogging, nor to the office i am bed ridden the pain is severe please...

Ask Question
Doctor Image

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

Related Drugs/Medications
Related Medical Topics