Mircera

What is Mircera?

Methoxy polyethylene glycol-epoetin beta is the active ingredient of a drug marketed by Hoffmann-La Roche under the brand name Mircera. Mircera is a long-acting erythropoietin receptor activator (CERA) indicated for the treatment of patients with anaemia associated with chronic kidney disease. It is the first approved, chemically modified erythropoiesis-stimulating agent (ESA). Mircera is supplied as a solution in pre-filled syringes for intravenous or subcutaneous administration. Mircera was approved for use in Europe in July 2007 by the European Commission, in September 2007 by the Swissmedic, and in November 2007 by the U.S. Food and Drug Administration for use in the United States.

Methoxy polyethylene glycol-epoetin beta is made from erythropoietin by chemically linking the N-terminal amino group or the Є-amino group of any lysine present in the protein with methoxy polyethylene glycol butanoic acid. The average molecular weight is approximately 60kDa. The drug stimulates erythropoiesis by interacting with the erythropoietin receptor on progenitor cells in the bone marrow.

Questions and answers on "Mircera"

My father has been detected CKD and has been advised to take certain medicines. His serum creatinine level is 2.8. the medicine prescribed to him...

doctor1 MD

IHi and welcome. I am not sure what is contained in DOXOVAt tablet?? Your dad seems to be on two erythropoietin preparations (Wepox and Mercera)...

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Hi, I am XXXXXXX My father has being suffering from body ache since 4-5 years now and his protein is coming out from his body because of which his...

doctor1 MD

Hi XXXXXXX

Thanks for posting your query.

I can appreciate your concern for your father.

There could be various reasons for weakness, body ache...

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Hello sir, both the kidneys of my aunt is damaged upto an extent of 80%

wanted an opinun on the case

few details mentioned below
Name of patient...

doctor1 MD

Brief Answer:
Supportive treatment in initial stage is required.

Detailed Answer:
Hello dear. From your description , she is suffering from chronic kidney disease...

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Recent questions on  Mircera

doctor1 MD

AOA, My father aged 63 weight 69 height 6feet now is suffering from hypertension since last 25+years and is also a heart patient since 1998. Since...

doctor1 MD

Hello sir, both the kidneys of my aunt is damaged upto an extent of 80% wanted an opinun on the case few details mentioned below Name of patient...

doctor1 MD

My father has been detected CKD and has been advised to take certain medicines. His serum creatinine level is 2.8. the medicine prescribed to him...

doctor1 MD

Hi, I am XXXXXXX My father has being suffering from body ache since 4-5 years now and his protein is coming out from his body because of which his...

doctor1 MD

1. How much long the Inj. Espogen 3000 IU is to be continued as it's availability is very difficult and my Doctor insist to come over his far...

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