Melphalan

What is Melphalan?

Melphalan (trade name Alkeran, in former USSR also known as Sarcolysin) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.

An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring.

Otherwise known as L-Phenylalanine Mustard, or L-PAM, melphalan is a phenylalanine derivative of mechlorethamine.

Questions and answers on "Melphalan"

I was diagnosed in 2007 with Multiple Myeloma, was treated with IV Velcade, Revlimid initially then had ASCT with high dose Mephalan. Remission...

doctor1 MD

Brief Answer:
HLA matched BMT is definitive treatment.

Detailed Answer:
Hi Sir,

I read your query and understand your concern.

MM in your case has...

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I am a multiple myeloma patient in the grade 3a and i want to ask about how to reduce the blood viscosity by medecine and food the plasma vicosity...

doctor1 MD

Hello,
High viscosity in myeloma is usually due to the activity of the disease (the "bad" plasma cells produce large quantities of abnormal...

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Im a 64 year-old athletic female, 95 lbs, 157 cm. recently sustained 3 stage 3 stress fractures during running and triathlon training. Was swimming...

doctor1 MD

Brief Answer:
Melanonychia

Detailed Answer:
Hi,

I have gone through your query and pictures of the nail.

There is a longitudinal dark band on your...

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Recent questions on  Melphalan

doctor1 MD

I was diagnosed in 2007 with Multiple Myeloma , was treated with IV Velcade, Revlimid initially then had ASCT with high dose Mephalan. Remission...

doctor1 MD

Im a 64 year-old athletic female, 95 lbs, 157 cm. recently sustained 3 stage 3 stress fractures during running and triathlon training. Was swimming...

doctor1 MD

I am a multiple myeloma patient in the grade 3a and i want to ask about how to reduce the blood viscosity by medecine and food the plasma vicosity...

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