What is Mellaril?

Thioridazine (Mellaril or Melleril) was a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis; it was withdrawn worldwide in 2005 because it caused severe cardiac arrhythmias.

In older references, it is sometimes described as atypical, but more recently it is usually described as typical, with the term "atypical" usually reserved for agents showing D4 selectivity or serotonin antagonism. The atypicality of second generation agents is not clearly defined. Some believe it's low D2 affinity, quick dissociation, 5-HT2A receptor antagonism, or all of the above. Its perceived atypical effects (namely its comparatively low propensity for extrapyramidal side effects) are likely the result of its potent anticholinergic effects.

Questions and answers on "Mellaril"

My autistic kid of 4 yes was prescribed mellaril (thioridaxine)5mg twice aday.we be given him the dose only for 3 days and now he keep on crying...

doctor1 MD

Thanks for the question. Your child is suffering from autism and such children at times need neurolept medications.
Thioridazine many a times...

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If you are taking Mellaril with tamoxifen, should the tamoxifen be increased above 20 mg because mellaril increases prolactin hormone levels?

I did...

doctor1 MD

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Detailed Answer:

Delighted to be able to help

The first thing to say that in some countries thioridazine sale was...

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Drug interactions between Seroquel, Valium, Cogentin. Urocholine, Prilosec, Rapaflo
Cogentin just added to regimen for person with autism, MR,...

doctor1 MD

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Detailed Answer:
Hello, and thanks for your question.

These drugs are all safe to use together -- there are no major...

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