What is Lomotil?

Comprehensive information about Lomotil and allied drugs is under the article Diphenoxylate.

The drug combination diphenoxylate/atropine (trade name Lomotil) is a popular oral anti-diarrheal in the United States, manufactured by Pfizer. Its UK BAN generic name is co-phenotrope.

Its active ingredients are diphenoxylate and atropine. Diphenoxylate is anti-diarrheal and atropine is anticholinergic. A subtherapeutic amount of atropine sulfate is present to discourage deliberate overdosage. Atropine has no anti-diarrheal properties, but will cause tachycardia when overused. The medication diphenoxylate works by slowing down the movement of the intestines. In some cases Lomotil has been shown to ease symptoms of opiate/opioid withdrawal.

The inactive ingredients of Lomotil (as a liquid; it comes in pill form as well) are cherry flavor, citric acid, ethyl alcohol 15%, FD&C Yellow No. 6, glycerin, sodium phosphate, sorbitol, and water.

Other trade names for the same therapeutic combination are Lofene, Logen, Lomanate and Lonox, among others. In other countries, Lomotil may have other names.

In the United States, Lomotil is classified as a Schedule V controlled substance by federal law, and is available only for a medical purpose.

Questions and answers on "Lomotil"

hi doc,I am Garima,i have loose motion from 2 days,its my fifth mont is running,yesterday i had tkn radotril bt no relax then my doc has changed n...

doctor1 MD

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I have noticed u dint mention about fever so I am assuming u don't have it. Take probiotics like nutrolin b or sporolac. Dont...

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my mom has been taking nexito forte for a month now and we think because of this - she is having symptoms of diarrea, having upto 6 -7 loose...

doctor1 MD

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Nexito forte contains escitalopram and clonazepam. Excitalopram is an antidepressant and is...

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I have just arrived back from XXXXX last night, during the flight i had sore stomach cramps which have got a lot worse, I have been in lots of pain...

doctor1 MD

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It seems that you have a viral gut infection. Symptomatic treatment involves taking tablet lomotil and plenty of...

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