What is Lioresal?

Baclofen, brand names include Gablofen among others, is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

It is a GABA receptor agonist, specifically for the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups.

A beneficial property of baclofen is that tolerance does not seem to occur to a significant degree — baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment.

Questions and answers on "Lioresal"

My father has had two operations on the spine - both to remove calcium deposits which were pressing the nerves. a plate and an expandable titanium...

doctor1 MD

Welcome to HCM
We understand your concerns

I went through your details. Every aged person goes through surgical procedure are supposed to be...

Read Full Thread   Ask a Doctor Now

I am a 67 yr. old woman, in a wheelchair (M.S.) overweight due to lack of exercise, cannot free stand or move out of the wheelchair without help. I...

doctor1 MD

Brief Answer:
Keep yourself motivated.

Detailed Answer:
Hi, thanks for writing to XXXXXXX

I suggest you to use elastic pressure graded stockings...

Read Full Thread   Ask a Doctor Now

Recent questions on Lioresal

Ask Question
Doctor Image

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

Related Drugs/Medications
Related Treatment/Therapy
Related Lab Tests
Related Procedures
Related Medical Topics