What is Hydroxocobalamin?

Hydroxocobalamin (also hydroxycobalamin, OHCbl, or B12a) is a natural form, or vitamer, of vitamin B12. It is a member of the cobalamin family of compounds. Hydroxocobalamin is produced by many bacteria that are used to produce the vitamin commercially. Like other forms of vitamin B12, hydroxocobalamin has an intense red color. In humans, it is rapidly converted to usable coenzyme forms of vitamin B12. Hydroxocobalamin is used as an injectable solution for treatment of the vitamin deficiency and for treatment for cyanide poisoning. It has been tested as a scavenger of nitric oxide.

"Vitamin B12" refers to a group of compounds called cobalamins that are available in the human body in a variety of mostly interconvertible forms. Together with folic acid, cobalamins are essential cofactors required for DNA synthesis in cells where chromosomal replication and division are occurring—most notably the bone marrow and myeloid cells. As a cofactor, cobalamins are essential for two cellular reactions:

  • the mitochondrial methylmalonyl-CoA mutase conversion of methylmalonic acid (MMA) to succinate, which links lipid and carbohydrate metabolism, and
  • the activation of methionine synthase, which is the rate-limiting step in the synthesis of methionine from homocysteine and 5-methyltetrahydrofolate.

Questions and answers on "Hydroxocobalamin"

sir, i am diagnosed by dyspepsia and fatty liver. for the past three months i m suffering from bloating stomach, anxiety, deep breath intention,...

doctor1 MD

Thank you for your query.

Thank you for the detailed history. What you are suffering from the common symptoms of Dyspepsia.

Dyspepsia is a...

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Dear sir since 6-8 m months I was feeling a tingling sensation on my left finger some time on left arm, and near left cervical also some times on...

doctor1 MD

Brief Answer:
Hydroxocobalamin injections

Detailed Answer:
Vitamin B12 is vital for the formation of red blood cells, as well as for the...

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