What is Humalog?

Insulin lispro (marketed by Eli Lilly and Company as "Humalog") is a fast acting insulin analog. It was first approved for use in the United States in 1996, making it the first insulin analog to enter the market.

Engineered through recombinant DNA technology, the penultimate lysine and proline residues on the C-terminal end of the B-chain are reversed. This modification does not alter receptor binding, but blocks the formation of insulin dimers and hexamers. This allowed larger amounts of active monomeric insulin to be immediately available for postprandial injections.

Insulin lispro has one primary advantage over regular insulin for postprandial glucose control. It has a shortened delay of onset, allowing slightly more flexibility than regular insulin, which requires a longer waiting period before starting a meal after injection. Both preparations should be coupled with a longer acting insulin for good glycemic control.

Questions and answers on "Humalog"

Hello, on oxygen normally 4 litres 24/7, diabetic among many other health issues.
Question is my sugar has been high for the last 24 hours..I count...

doctor1 MD

Hi, welcome to our site. I am Dr Saumya Mittal.

Read your query. That is a very significant question and i appreciate your problem. I will try my...

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I am T1 diabetic since last 33 years. I am now taking 3 shots of HUmalog before meals and lantus at after dinner, my question is this my sugars...

doctor1 MD


Welcome to HCM,

I really appreciate taht you are taking care of your Type I Diabetes, you are taking basal insulin as well as Humalog ,if you...

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