Fortamet

What is Fortamet?

Metformin (BAN, USAN and INN, pronounced , ; sold as Glucophage) is an oral antidiabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function. Its use in gestational diabetes has been limited by safety concerns. It is also used in the treatment of polycystic ovary syndrome, and has been investigated for other diseases where insulin resistance may be an important factor. Metformin works by suppressing glucose production by the liver.

Limited evidence suggests metformin may prevent the cardiovascular and possibly the cancer complications of diabetes. Metformin is one of only two oral antidiabetics in the World Health Organization Model List of Essential Medicines (the other being glibenclamide).

Metformin causes few adverse effects when prescribed appropriately (the most common is gastrointestinal upset) and has been associated with a low risk of having a low blood sugar. Lactic acidosis (a buildup of lactate in the blood) can be a serious concern in overdose and when it is prescribed to people with contraindications, but otherwise, no significant risk exists.

First synthesized and found to reduce blood sugar in the 1920s, metformin was forgotten for the next two decades as research shifted to insulin and other antidiabetic drugs. Interest in metformin was rekindled in the late 1940s after several reports that it could reduce blood sugar levels in people, and in 1957, French physician Jean Sterne published the first clinical trial of metformin as a treatment for diabetes. It was introduced to the United Kingdom in 1958, Canada in 1972, and the United States in 1995. Metformin is now believed to be the most widely prescribed antidiabetic drug in the world; in the United States alone, more than 48 million prescriptions were filled in 2010 for its generic formulations.

Questions and answers on "Fortamet"

I get a migraine that is a 10 everyday within an hour of taking metformin ER 500 mg. I was taking fortamet ER 500 mg and did not get the migraine....

doctor1 MD

Hi
I read your question and understand your concern
I am sorry for the convenience with your treatment
In my opinion as I treat my migraine patient...

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My primary care physician put me on Fortamet, Onglyza, Glimipiride and Lantus (Insulin) in order to control my Type 2 Diabetes. She feels I do...

doctor1 MD

Brief Answer:
Go with your endocrinologist.

Detailed Answer:
Dear Madam,

Thank you for posting your query on XXXXXXX

Well I think you should go...

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I injured my shoulder while body surfing and then aggravated the injury while canoeing a few weeks later. This resulted in two X-rays which...

doctor1 MD

Hello,
Thanks for posting your query.
Clavicular lymph nodes are usually 0.5 to 0.8 cm in size. The size that has been mentioned in the MRI is...

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Recent questions on  Fortamet

doctor1 MD

I get a migraine that is a 10 everyday within an hour of taking metformin ER 500 mg. I was taking fortamet ER 500 mg and did not get the migraine....

doctor1 MD

My primary care physician put me on Fortamet , Onglyza, Glimipiride and Lantus ( Insulin ) in order to control my Type 2 Diabetes . She feels I do...

doctor1 MD

I injured my shoulder while body surfing and then aggravated the injury while canoeing a few weeks later. This resulted in two X-rays which...

doctor1 MD

I injured my shoulder while body surfing and then aggravated the injury while canoeing a few weeks later. This resulted in two X-rays which...

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