What is Estrace?

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. ' (oistros, literally meaning "verve or inspiration") and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations. Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.

Questions and answers on "Estrace"

I've been using Estrace cream 1gm/twice week. This is week 5. It has set me on fire-- labial redness and inflammation, minor itch. I assume this is...

doctor1 MD

You have not mentioned your age, Estrace is particularly given for dry and itchy vagina due to menopause, you have labial symptoms so this would...

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Im taking .5 estrace in the morning and 100 mg promterium. Hot flashes and night sweats disappeared after a few weeks but my night sweats...

doctor1 MD

Hi. Welcome to HCM. Estrace and prometrium contains females hormones estrogen and progesterone in synthetic forms. Estrace is used by women to help...

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Hi my Dr is putting me on Estrace cream, I am 59 with all the post menopause symptons, my estrogen level is 80 and he wantes it to be 150,, this...

doctor1 MD

It sounds the hormone replacing therapy ! no need for this, it is better to keep your self away from these level of estrogen,, what ever the...

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