What is Echinocandin?

Echinocandins are antifungal drugs that inhibit the synthesis of glucan in the cell wall, via noncompetitive inhibition of the enzyme 1,3-β glucan synthase and are thus called "penicillin of antifungals" (a property shared with papulacandins) as penicillin has a similar mechanism against bacteria but not fungi. Beta glucans are carbohydrate polymers that are cross-linked with other fungal cell wall components (The bacterial equivalent is peptidoglycan). Caspofungin, micafungin, and anidulafungin are semisynthetic echinocandin derivatives with clinical use due to their solubility, antifungal spectrum, and pharmacokinetic properties.

Questions and answers on "Echinocandin"

Hello Doctor,
We live in Coimbatore. My colleague's father is affected by some kind of Fungal Sinus. Last month there was a heavy swelling in the...

doctor1 MD


Thank you for your query.

1. From your description, he seems to have developed Invasive Fungal Sinusitis. The most common fungus is Mucor...

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I have candidal pneumonia that fluconazole won't treat anymore. I'm looking at buying Mycafungin online, can you recommend a...

doctor1 MD

Brief Answer:
100 mg/day. IV infusion over a period of 1 hour

Detailed Answer:
Hi Grahammoule, Thanks for using XXXXXXX

Micafungin can be given in...

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