What is Dolasetron?

Dolasetron (trade name Anzemet) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.

Dolasetron breaks down slowly, staying in the body for a long time. One dose usually lasts 4 to 9 hours and is usually administered once or twice daily. This drug is removed from the body by the liver and kidneys.

Questions and answers on "Dolasetron"

I have been diagnosed with typhoid 2 days ago. The night prior to diagnosis i collapsed and struck my head on the floor. I am taking Zythromycin...

doctor1 MD

hi nausea and vomiting are the commonest side effects of any drug but if it is severe enough it may also due to high fever like typhoid or...

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