Cycloserine

What is Cycloserine?

Cycloserine (4-amino-3-isoxazolidinone) is a drug sold under the brand name Seromycin. It is an antibiotic effective against Mycobacterium tuberculosis. Since the discovery that cycloserine is able to penetrate into the central nervous system, numerous studies have been conducted to assess the efficacy of cycloserine for psychiatric disorders. It has been found to be effective in the treatment of some neurological disorders, due to its effect as a selective partial agonist of the ''N''-methyl-D-aspartic acid (NMDA) glutamatergic receptors found in the basolateral nucleus of the amygdala. Specifically, cycloserine affects the glycine-binding sites which are important for opening these NMDA channels.

The name "cycloserine" is a misnomer because the compound has an extra nitrogen atom compared to serine. (It also has one fewer oxygen atom and one fewer hydrogen atom than serine.)

Questions and answers on "Cycloserine"

hello
i am XXXXXXX i am tb patient (mdr--tb).....presently i am on course from last 2 years using list of medicine as follows 1)pza 1000+750
2)combutol...

doctor1 MD

Brief Answer:
MDR-TB and HIV infection

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.

Since you have already taken...

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hi my name is manzar hussain m from darjeeling in west bengal india i have a query related to y younger brother. Actually he is having a problem of...

doctor1 MD

Hello and welcome to HCM
You have mentioned that your doctor has prescribed Coxerin (Cyloserine) and L-cin (Levofloxacin).
There are two sets of...

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