What is Combipatch?

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. ' (oistros, literally meaning "verve or inspiration") and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations. Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.

Questions and answers on "Combipatch"

what is the best way to stop using the combipatch? I stopped cold XXXXXXX two days ago and I feel...

doctor1 MD

Thanks for your health query.
Following removal of the combipatch will result in immediate drop in the hormone levels, and hence might leave...

Read Full Thread   Ask a Doctor Now

Hi , I was on the low dose combipatch and kept spotting everyday so they gave me the higher dose of it. well that was a mistake because the...

doctor1 MD


There is nothing to worry. You have to start tablets containing tranaxemic acids and mefenamic acids to stop bleeding.

Hope I have answered...

Read Full Thread   Ask a Doctor Now

I have just started this hormone replacement patch called combipatch
and my Dr. didn't tell me much about it....
I was wondering if I can take my...

doctor1 MD


Combipatch (skin patch) is a combination medicine used to treat menopause symptoms

Sometimes it is not safe to use certain medications at...

Read Full Thread   Ask a Doctor Now

Recent questions on Combipatch

Ask Question
Doctor Image

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

Related Drugs/Medications
Related Medical Topics