What is Colistimethate?

Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic. It is commercially available as 'Xylistin' (India, marketed by CIpla Pharmaceuticals ltd) and 'Koolistin' (India, registered and marketed by Biocon ltd)

Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity. It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter. NDM-1 metallo-β-lactamase multidrug-resistant Enterobacteriaceae have also shown susceptibility to Colistin.

Questions and answers on "Colistimethate"

Very soon after my mother had radiation treatment to her lungs she caught the pseudomonas bacteria in her lungs. She has been put on colistimethate...

doctor1 MD

hi welcome to HCM
i am concerned about your mothers health problem
itching and chest pain might be a side effect of colistin she is taking in...

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