What is Cetilistat?

Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.

In human trials, cetilistat was shown to produce similar weight loss to orlistat, but also produced similar side effects such as oily, loose stools, fecal incontinence, frequent bowel movements, and flatulence. It is likely that the same precautions would apply in that absorption of fat-soluble vitamins and other fat-soluble nutrients may be inhibited, requiring vitamin supplements to be used to avoid deficiencies.

Questions and answers on "Cetilistat"

i am under the medication of weight reduction since 1 month. since 1 week i noticed that my stool has oily nature. is there any problem from this?....

doctor1 MD

Welcome to HealthcareMagic

If stools appear oily or oddly colored over a period of days or longer, then the cause may be medical in nature.


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Hi Doc..my name is XXXXXXX I am 33 yrs/ F/weight 105 kg/ height 167 cm.i took Xenical for 6-7 months. Initially with right diet and exercise I lost...

doctor1 MD

Thanks for writing in to Healthcare magic!
You are facing the after effects of weight reducing drugs.
The orlistat and other related...

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