What is Cesamet?

Nabilone is a synthetic cannabinoid with therapeutic use as an antiemetic and as an adjunct analgesic for neuropathic pain. It mimics tetrahydrocannabinol (THC), the primary psychoactive compound found naturally occurring in Cannabis.

In Canada, the United States, the United Kingdom and Mexico, nabilone is marketed as Cesamet. It was approved in 1985 by the U.S. Food and Drug Administration (FDA) for treatment of chemotherapy-induced nausea and vomiting (CINV) that has not responded to conventional antiemetics. Though it was approved by the FDA in 1985, the drug only began marketing in the United States in 2006. In Austria Nabilone is marketed as Canemes and got its approval for CINV in 2013.

Although it doesn't have any indication officially (except in Mexico), nabilone is widely used as an adjunct therapy for chronic pain management. Numerous trials and case studies have demonstrated modest effectiveness for relieving fibromyalgia and multiple sclerosis.

Nabilone is a racemic mixture consisting of the (S,S) and the (R,R) isomers ("trans").

Questions and answers on "Cesamet"

I have been on Cesamet - 5 mg (was on 7) for chronic pain since 2005. I am trying to come off the drug - was recommended to come down 1 mg every 2...

doctor1 MD

Thanks for the query.
CESAMET is a cannabinoid and can causes addiction when used for such a long time as you have used.
It's withdrawl...

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41 year old male, short of breath upon mild exertion, profuse sweating, tingling hands feet, chest tightness feeling weak, tired no energy ....

doctor1 MD


I am dr XXXXXXX and I will try my level best to help you.

The symptoms such as tingling hands feet,feeling weak,chest pain, irregular heart...

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