What is Bromfenac?

Bromfenac is a non-steroidal anti-inflammatory drug (NSAID) marketed in the US as an ophthalmic solution (current brand names Prolensa and Bromday, prior formulation brand name Xibrom, which has since been discontinued.) by ISTA Pharmaceuticals for short-term, local use. Prolensa and Bromday are the once-daily formulation of bromfenac, while Xibrom was approved for twice-daily administration. Bromfenac is indicated for the treatment of ocular inflammation and pain after cataract surgery, though it may be prescribed in an off-label manner by the physician.

For ophthalmic use, bromfenac has been prescribed more than 20,000,000 times across the world. As an eye drop, it has been available since 2000, starting in Japan where it was sold as Bronuck. It was first FDA approved for use in the United States in 2005, and it was marketed as Xibrom, twice-daily. In October 2010 Bromday received FDA approval as a new, once-daily formulation. More recently, in 2013, Prolensa has also been approved by the FDA. The bromfenac molecule will be marketed in Europe and other worldwide markets with agreements from Bausch & Lomb, Croma Pharma, and other companies.

Bromfenac was formerly marketed in the United States by Wyeth-Ayerst in an oral formulation called Duract for short-term relief of pain (less than 10 days at a time). It was brought to market in July, 1997, and was withdrawn June 22, 1998 following numerous reports of hepatotoxicity in patients who had taken the medication for longer than the recommended 10-day period. The dose was one 25 mg capsule every 6 to 8 hours, or two capsules if taken with a high-fat meal, up to a maximum of 150 mg per day.

Questions and answers on "Bromfenac"

line visiableI had my eyeoperadfor cataract and retina meembrane by a most sr eye specilist.But I have onythreelinesvisiable please sdoctor advised...

doctor1 MD

Brief Answer:
Post operative eye pain.

Detailed Answer:
Thanks for asking on HealthcareMagic.

I have gone carefully through your query and...

Read Full Thread   Ask a Doctor Now

So for the last 2-3 days my caruncle of my right eye has been a little bit itchy and kinda burning a little bit. It also feels slightly swollen and...

doctor1 MD

Brief Answer:
It looks like inflammation of caruncle.

Detailed Answer:
Welcome to Health care magic.

I am Dr. Dadapeer K, an ophthalmologist...

Read Full Thread   Ask a Doctor Now

I am scheduled to have cataract surgery at 6:15 a.m. on Monday, Oct 28
My doctor prescribed three types of eye drops to be used Saturday and...

doctor1 MD

Thank you for asking question on health care magic
Probably they have marked wrongly
They have prescribed 4 drops instead of 4 times a day

Read Full Thread   Ask a Doctor Now

Recent questions on Bromfenac

Ask Question
Doctor Image

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

Related Disease & Conditions
Related Lab Tests
Related Medical Topics