Avinza

What is Avinza?

Morphine (INN) () (sold under nearly a hundred trade names) is an opioid analgesic drug. It is the main psychoactive chemical in opium. Like other opioids, such as oxycodone, hydromorphone, and heroin, morphine acts directly on the central nervous system (CNS) to relieve pain.

Morphine has a high potential for addiction; tolerance and psychological dependence develop rapidly, although physiological dependence may take several months to develop. Tolerance to respiratory depression and euphoria develops more rapidly than tolerance to analgesia, and many chronic pain patients are therefore maintained on a stable dose for years. However, its effects can also reverse fairly rapidly, worsening pain through hyperalgesia.

Morphine is the most abundant opiate found in opium, the dried latex from unripe seedpods of Papaver somniferum (the opium poppy). Morphine was the first active ingredient purified from a plant source. It is one of at least 50 alkaloids of several different types present in opium, poppy straw concentrate, and other poppy derivatives. The primary source of morphine is chemical extraction from opium. It is a Schedule II drug in the United States, Class A in the United Kingdom, and Schedule I in Canada.

Morphine was first isolated in 1804 by Friedrich Sertürner, which is generally believed to be the first ever isolation of a natural plant alkaloid in history. Sertürner began distributing it in 1817, and Merck began marketing it commercially in 1827. At the time, Merck was a single small chemists' shop. Morphine was more widely used after the invention of the hypodermic syringe in 1857. Sertürner originally named the substance morphium after the Greek god of dreams, Morpheus (), for its tendency to cause sleep. It is on the WHO Model List of Essential Medicines, a list of the most important medications needed in a basic health system.

Questions and answers on "Avinza"

I have severe spinal stenosis ,spondylolthesis with pars defect spondylosis and chronic tendinitis in both shoulders.i was taking 90 mil of Avinza...

doctor1 MD

Hello,

Thanks for writing to us.

I am Dr vaibhav Gandhi, I am orthopaedic surgeon and spine specialist.
I have studied your case.

This kind of pain...

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If I switch from Avinza 90 ER to Xartemis 7.5 ER (X two twice a day) do you think I will experience withdrawals if I...

doctor1 MD

Brief Answer:
This is unlikely..Howeverm tapper of while you intriduce the new medication

Detailed Answer:
Hi and thank you so much for this query....

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Hi - I just had my blood checked for kidney and liver function because I'm on meds for a chronic back injury. My creatinine level is 1.17 and BUN...

doctor1 MD

Brief Answer:
No need to worry.

Detailed Answer:
Hello!

Thank you for the query.

This medicines in regular dosages should not affect kidneys.
Your...

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Recent questions on  Avinza

doctor1 MD

I am a chronic pain patient with my spine. Had two failed surgeries. My new pain doc took me down from 90 mg avinza 2 times daily which was working...

doctor1 MD

If I switch from Avinza 90 ER to Xartemis 7.5 ER (X two twice a day) do you think I will experience withdrawals if I swich.

doctor1 MD

I've been on Avinza for chronic pain for a few years now. Was at 240mgq at my XXXXXXX then went to 180mgs, then to 120mgs, then to 80mgs, down to...

doctor1 MD

I have severe spinal stenosis ,spondylolthesis with pars defect spondylosis and chronic tendinitis in both shoulders.i was taking 90 mil of Avinza...

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