What is Asacol?

Mesalazine (INN, BAN), also known as mesalamine (USAN) or 5-aminosalicylic acid (5-ASA), is an anti-inflammatory drug used to treat inflammatory bowel disease, such as ulcerative colitis and mild-to-moderate Crohn's disease. Mesalazine is a bowel-specific aminosalicylate drug that acts locally in the gut and has its predominant actions there, thereby having few systemic side effects.

As a derivative of salicylic acid, mesalazine is also thought to be an antioxidant that traps free radicals, which are potentially damaging byproducts of metabolism.

Mesalazine is the active moiety of sulfasalazine, which is metabolized to sulfapyridine and mesalazine.

Mesalazine is the active component of the prodrug balsalazide along with the inert carrier molecule 4-aminobenzoyl-beta-alanine.

Questions and answers on "Asacol"

Could loss of appetite and nausea be caused by missing dosages of asacol? I am supposed to take 5 tablets (400mg) twice daily and I sometimes miss...

doctor1 MD

Asacol 400 mg tablets contain the active substance melsalazine which is an anti-inflammatory drug used in the treatment of Ulcerative colitis...

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brother diagnosed with uc 7 yrs ago. he is hospitalized currently since they can't seem to get his symptoms of uc under control. takes asacol,...

doctor1 MD


Thank you for trusting HCM

Dear ulcerative colitis treatment depends upon the severity of the disease, associated complications etc..


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i was diagnoised with ulcerative colitis in 1997 3 wks ago i started a new thyroid medicine called tirosint 25mcg one daily i began to have stomach...

doctor1 MD


Thanks for the query

You are on the right medications for the ulcerative colitis, please continue taking them. For the pain may I also...

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