Analgin

What is Analgin?

Metamizole (INN), or dipyrone (BAN, USAN), is an ampyrone sulfonate analgesic (pain reliever), antispasmodic (spasm reliever) and antipyretic (fever reducer) similar to paracetamol in that it has minimal anti-inflammatory effects and which is most commonly given orally or parenterally (by injection) to prevent and treat pain related to surgery or for the treatment of acute pain. although in some countries it is available over-the-counter, its use is usually restricted in developed countries, due to its potential for causing toxic reactions.

Metamizole is marketed under various trade names, including Algozone, Algocalmin, Algopyrin, Analgin, Dipirona, Novalgin, Neo-Melubrina and Optalgin.

It was once widely combined with various other active ingredients, but since concerns over its safety have been raised in the late 1960s and 1970s its use in combination products has been in decline and in some countries, banned. Regardless, some national medical authorities (such as in Australia and United States of America) have withdrawn metamizole from the market altogether or have restricted it to be available only with a prescription, although it remains available over the counter in some countries.

Despite its potential haematologic (blood-related) toxicity (that is potential for causing blood dyscrasias) it produces no clinically relevant effects in the way of kidney toxicity, cardiovascular toxicity and GI toxicity when compared to non-steroidal anti-inflammatory drugs (NSAIDs). Unlike paracetamol and similarly to the NSAIDs it can trigger bronchospasm or anaphylaxis, especially in those with asthma.

Questions and answers on "Analgin"

Dear Doctor, I am aged 53 from Delhi suffering from Migraine since chidhood.The frequency at age between 20-40 was very high around twice a...

doctor1 MD

Hello,
Thanks for posting your query.
As you have long history of recurrent migraine and it is well controlled by drugs like Vasogrin & Analgin....

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29 years aged male administered novalgin 500 mg. , brufen 600 , panadol 500, and 100 mg anafranil as two 50 mg. tablets after a breakfast, but the...

doctor1 MD

Hi,

This guy has taken too much medicines for pain (3 strong pain-killers). He should have taken panadol first, then, if after 4 hours no relief,...

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Dear Doctor. Am 20 years old man. I got report of MRI today written: "There is an oval shaped faintly intense T2 and hypointense T1 focus
in the...

doctor1 MD

Brief Answer:
Several possibilities.

Detailed Answer:
I read your question carefully and I understand your concern.

It would have been helpful to...

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Recent questions on  Analgin

doctor1 MD

My wife is experiencing sharp shooting pains in her breast. It radiates from deep in the breast and out through her nipple. What could this be? It...

doctor1 MD

Dear Doctor. Am 20 years old man. I got report of MRI today written: "There is an oval shaped faintly intense T2 and hypointense T1 focus in the...

doctor1 MD

I am suppose to take Robaxin for my back pain but am in Russia - is there a Russian equivalant?

doctor1 MD

29 years aged male administered novalgin 500 mg. , brufen 600 , panadol 500, and 100 mg anafranil as two 50 mg. tablets after a breakfast, but the...

doctor1 MD

Dear Doctor, I am aged 53 from Delhi suffering from Migraine since chidhood.The frequency at age between 20-40 was very high around twice a...

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