Amorolfine

What is Amorolfine?

Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes. Marketed as Curanail, Loceryl, Locetar, and Odenil, amorolfine is commonly available in the form of a nail lacquer, containing 5% amorolfine as the active ingredient. It is used to treat onychomycosis (fungal infection of the toe- and fingernails). Amorolfine 5% nail lacquer in once-weekly or twice-weekly applications has been shown in two studies to be between 60% and 71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment) were 38% and 46%. However, full experimental details of these trials were not available and since they were first reported in 1992 there have been no subsequent trials.

Questions and answers on "Amorolfine"

I have a toenail fungus. I need to be prescribed a topical med. to treat it. Can you prescribe Jublia or another med. to me for treatment?

doctor1 MD


Hi
Thanks for being at Healthcaremagic
Topical antifungals that are effective in toe nail fungal infection are amorolfine nail lacquer and...

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I have an infection of the big toe nail, probably caused by a fungus. What can I do?

doctor1 MD

Brief Answer:
Go for oral antifungals

Detailed Answer:
Hi
Thanks for being at HealthcareMagic
For fungal nail infection you need to take oral...

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what is the skin condition and how should I get rid of this.its etching sometimes. its on middle aspects of thigh and upper limb

doctor1 MD

Brief Answer:
Appears to be mild fungal infection of the affected area.

Detailed Answer:
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Welcome and thanks for posting your query to the...

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Recent questions on  Amorolfine

doctor1 MD

I have a toenail fungus. I need to be prescribed a topical med. to treat it. Can you prescribe Jublia or another med. to me for treatment?

doctor1 MD

Hi doctor, i am attaching the photo of my toe.its very rough and uneven.and have got lines in between.so can you pls guide .i hope it doesnt break.

doctor1 MD

I have an infection of the big toe nail, probably caused by a fungus. What can I do?

doctor1 MD

hi,Im 21 years old.Im suffering from fungus infection on my toe nail and have consulted a dermatologist who prescribed me nail lacquer which is...

doctor1 MD

I have an unsightly toenail fungus on six toes. For a year I have used Batafren lacquer and covered it with a coloured nail lacquer. There is no...

doctor1 MD

Hi, Ok so im a nail tech and I do pedicures. I just had a client in with fungus on all her toe nails . I advised her to see a podiatrist cause im...

doctor1 MD

i have nail fungal last 5 yrs , i am useing nuforce 150 but i did not get complete cure . plz suggest me

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