Amorolfine

What is Amorolfine?

Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes. Marketed as Curanail, Loceryl, Locetar, and Odenil, amorolfine is commonly available in the form of a nail lacquer, containing 5% amorolfine as the active ingredient. It is used to treat onychomycosis (fungal infection of the toe- and fingernails). Amorolfine 5% nail lacquer in once-weekly or twice-weekly applications has been shown in two studies to be between 60% and 71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment) were 38% and 46%. However, full experimental details of these trials were not available and since they were first reported in 1992 there have been no subsequent trials.

Questions and answers on "Amorolfine"

I have a toenail fungus. I need to be prescribed a topical med. to treat it. Can you prescribe Jublia or another med. to me for treatment?

doctor1 MD


Hi
Thanks for being at Healthcaremagic
Topical antifungals that are effective in toe nail fungal infection are amorolfine nail lacquer and...

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I have an infection of the big toe nail, probably caused by a fungus. What can I do?

doctor1 MD

Brief Answer:
Go for oral antifungals

Detailed Answer:
Hi
Thanks for being at HealthcareMagic
For fungal nail infection you need to take oral...

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what is the skin condition and how should I get rid of this.its etching sometimes. its on middle aspects of thigh and upper limb

doctor1 MD

Brief Answer:
Appears to be mild fungal infection of the affected area.

Detailed Answer:
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Welcome and thanks for posting your query to the...

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