Trophoblastic disease

What is Trophoblastic disease?

Gestational trophoblastic disease (GTD) is a term used for a group of pregnancy-related tumours. These tumours are rare, and they appear when cells in the womb start to proliferate uncontrollably. The cells that form gestational trophoblastic tumours are called trophoblasts and come from tissue that grows to form the placenta during pregnancy.

There are several different types of GTD. Hydatidiform moles are, in most cases, benign, but may, sometimes, develop into invasive moles, or, in rare cases, into choriocarcinoma, which is likely to spread quickly, but which is very sensitive to chemotherapy, and has a very good prognosis. Gestational trophoblasts are of particular interest to cell biologists because, like cancer, these cells invade tissue (the uterus), but unlike cancer, they sometimes "know" when to stop.

GTD can simulate pregnancy, because the uterus may contain fetal tissue, albeit abnormal. This tissue may grow at the same rate as a normal pregnancy, and produces chorionic gonadotropin, a hormone which is measured to monitor fetal well-being.

While GTD overwhelmingly affects women of child-bearing age, it may rarely occur in postmenopausal women.

Questions and answers on "Trophoblastic disease"

Worry about getting Gestational Trophoblastic Disease.

I am now at age 40, my last menstrual date was 29 March 2015 and I was diagnosed a missed...

doctor1 MD

Brief Answer:
Trophoblastic disease is less likely.

Detailed Answer:
Hello,
Thanks for trusting us with your health concern.
After a miscarriage it...

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Hi i have been havung chemo for gestation trophoblastic disease and i am under alot of stress could i be expirienceing an nervouus breakdown?...

doctor1 MD

Brief Answer:
Hi and welcome to XXXXXXX

Detailed Answer:
Yes,it may be nervous breakage which is understandable and common in cases of such serious...

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Dears ,,,

I am writing this message from Saudi Arabia , my wife was pregnant and before one month while she is having her second month follow up...

doctor1 MD

Hello,

Thanks for writing to us on Healthcare Magic.

First thing, partial vesicular mole (Hydatidiform mole) is one type of Gestational Trophoblastic Disease...

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Recent questions on  Trophoblastic disease

doctor1 MD

Worry about getting Gestational Trophoblastic Disease . I am now at age 40, my last menstrual date was 29 March 2015 and I was diagnosed a missed...

doctor1 MD

my daughter is 20 yrs of age and just given birth 3.5 months ago has been diagnosed 12 yrs ago with a garter duct cyst on the wall of her uterus ....

doctor1 MD

Hi i have been havung chemo for gestation trophoblastic disease and i am under alot of stress could i be expirienceing an nervouus breakdown?...

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