What is Thrombasthenia?

Glanzmann's thrombasthenia is an abnormality of the platelets. It is an extremely rare coagulopathy (bleeding disorder due to a blood abnormality), in which the platelets contain defective or low levels of glycoprotein IIb/IIIa (GpIIb/IIIa), which is a receptor for fibrinogen. As a result, no fibrinogen bridging of platelets to other platelets can occur, and the bleeding time is significantly prolonged.

Questions and answers on "Thrombasthenia"

Dear Sir, my wife is suffering from Glanzmans Thrombostania since 1992, we married in 1994 till childless, tried IVF 8 times with Dr. Malpani, Dr....

doctor1 MD

Glanzmann thrombasthenia is a genetic platelet disorder in which the platelet glycoprotein IIb/IIIa (GP IIb/IIIa) complex is either deficient or...

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Hi, my 7 year old son woke up with a petechiae rash on the right side of his chest. There are a couple of raised bumps that are itchy between the...

doctor1 MD

In any child with petechiae rash ,low platelet number(thrombocytopenia) or function (thrombasthenia)should be ruled out along leaky...

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I have a sudden bruising on my right bicep. I have done nothing physical to cause it.

doctor1 MD

Brief Answer:
Bleeding into the skin ought to be investigated

Detailed Answer:

The bruising or bleeding into the skin without trauma can...

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