Thiamine deficiency

What is Thiamine deficiency?

Thiamine, thiamin or vitamin B1 ( ), named as the "thio-vitamine" ("sulfur-containing vitamin") is a vitamin of the B complex. First named aneurin for the detrimental neurological effects if not present in the diet, it was eventually assigned the generic descriptor name vitamin B1. Its phosphate derivatives are involved in many cellular processes. The best-characterized form is thiamine pyrophosphate (TPP), a coenzyme in the catabolism of sugars and amino acids. In yeast, TPP is also required in the first step of alcoholic fermentation.

All living organisms use thiamine, but it is synthesized only in bacteria, fungi, and plants. Animals must obtain it from their diet, and thus, for humans, it is an essential nutrient. Insufficient intake in birds produces a characteristic polyneuritis. In mammals, deficiency results in Korsakoff's syndrome, optic neuropathy, and a disease called beriberi that affects the peripheral nervous system (polyneuritis) and/or the cardiovascular system. Thiamine deficiency has a potentially fatal outcome if it remains untreated. In less severe cases, nonspecific signs include malaise, weight loss, irritability and confusion.

The stable and non-hygroscopic salt thiamine mononitrate is the vitamer used for flour and food fortification. Thiamine is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Questions and answers on "Thiamine deficiency"

Is thiamine deficiency during pregnancy reversible? Does the infant suffer from thiamine...

doctor1 MD

Brief Answer:
There is not much evidence available about thiamine deficiency in pregnancy

Detailed Answer:
Hello, and I hope I can help you today....

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I feel occasionally jhanjhanahat in my fingers, legs and hands which remain for few seconds. I often remain in stress....

doctor1 MD

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Jhanjhanat (tingling) in hands and feet is usually a sign of...

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Would drinking heavily 2 days a week over many years delplete me of B vitamins or other vitamins?

doctor1 MD

Brief Answer:
Pretty much unquestionably

Detailed Answer:
It's primarily folic acid and thiamine.
First, it matters a lot what the rest of the...

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