Primary ciliary dyskinesia

What is Primary ciliary dyskinesia?

Primary ciliary dyskinesia (PCD), also known as immotile ciliary syndrome, is a rare, ciliopathic, autosomal recessive genetic disorder that causes a defect in the action of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube, as well as the flagella of sperm cells.

Respiratory epithelial motile cilia, which resemble microscopic "hairs" (although structurally and biologically unrelated to hair), are complex organelles that beat synchronously in the respiratory tract, moving mucus toward the throat. Normally, cilia beat 7 to 22 times per second, and any impairment can result in poor mucociliary clearance, with subsequent upper and lower respiratory infection. Cilia also are involved in other biological processes (such as nitric oxide production), which are currently the subject of dozens of research efforts. As the functions of cilia become better understood, the understanding of PCD should be expected to advance.

Questions and answers on "Primary ciliary dyskinesia"

Hello, my son is 10 year old premature birth at 36 weeks. Was born with a PFO which closed, but he has a sub aortic membrane and now they have...

doctor1 MD

Brief Answer:
To Rule out primary ciliary dyskinesia

Detailed Answer:
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Dear Ms,

Being a parent...

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Hi Doctor , Iam trying to conceive from past 2and half years.but i didn t conceive yet. I have Kartageners Syndrome - Situs Inverses. Iam 27 years...

doctor1 MD

The Kartageners Syndrome got Situs Inversus, Chronic Sinusitis and Bronchiactasis. It can cause occational sterility in males. It does not effect...

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my wife under went a 24 week anomoly scan today and the scan says situs inversus totalis. Is it safe to continue pregnancy. can the child born...

doctor1 MD


Thank you for posting your query.

Situs inversus totalis is a condition where major visceral organs inside the body are reversed...

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