Periodic fever syndrome
What is Periodic fever syndrome?
These syndromes refer to diseases that cause periodic (episodic) fever that do not have an infectious (virus, bacteria) cause. In general children with these syndromes are well between episodes. Many of these syndromes are hereditary (passed down from parents) and result from a mutation (defect or mistake) in a gene (this is the code that determines the structure of our proteins). The syndromes are defined by the gene defect as well as by the clinical features of the syndrome, the parts of the body affected in addition to fever, the age of the child when the syndrome starts, and the ethnicity (the area of the world where the child or parents come from) of the child and parents. Many of these syndromes have a specific treatment, often based on understanding the problem caused by the genetic defect.
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