Osteopetrosis

What is Osteopetrosis?

Excessive formation of dense trabecular bone and calcified cartilage, especially in long bones, leading to obliteration of marrow spaces and to anemia with myeloid metaplasia and hepatosplenomegaly beginning in infancy, to bone fragility, and to progressive deafness and blindness; autosomal dominant inheritance. There are also autosomal recessive forms, which may be mild [MIM*259710], severe [MIM*259700], or lethal [MIM*259720], and sometimes involve a renal tubular defect [MIM*259730]. A milder, autosomal dominant form has onset in childhood and no neurologic sequelae.

Questions and answers on "Osteopetrosis"

Dear Doctor, I have a patient with infected nonunion fracture shaft femur with osteopetrosis. was operated 4 years back with DCP, got infected...

doctor1 MD

hi,

thank-you for providing the brief history.

As the surgery was failure trying the trying the iliazarov ring fixator should work well but may...

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Hi, I am 49 years of age, 160cm, 73 kg. i have an hereditary bone disease, osteopetrosis which causes me to break bones easily and gives me...

doctor1 MD

Dear,

Thanks for your query.

Established procedure for diabetic retinopathy is to have flourocine angiography followed by laser photocoagulation....

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I am a dangerously obsese (325lbs/5'3"), female with pulmonary hypertension, arthritis, type 2 diabetes,
thyroid problems and very limited...

doctor1 MD

Brief Answer:
Hi

Detailed Answer:
Good dear,

Noted your concerns. Is the bone condition what you are mentioning Osteopetrosis or PAget's disease ?...

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Recent questions on  Osteopetrosis

doctor1 MD

Dear Doctor, I have a patient with infected nonunion fracture shaft femur with osteopetrosis. was operated 4 years back with DCP, got infected...

doctor1 MD

My daughter is 10 and a half months old She has not got any teeth yet Is it normal? What is the normal time to get teeth ? Otherwise everything...

doctor1 MD

I am a dangerously obsese (325lbs/5'3"), female with pulmonary hypertension , arthritis , type 2 diabetes , thyroid problems and very limited...

doctor1 MD

My son has suffered from multiple fractures. His Vitamin D levels have remained below 20 despite giving him supplements and making him go out in...

doctor1 MD

Hi, I am 49 years of age, 160cm, 73 kg. i have an hereditary bone disease , osteopetrosis which causes me to break bones easily and gives me...

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