Osteopetrosis

What is Osteopetrosis?

Excessive formation of dense trabecular bone and calcified cartilage, especially in long bones, leading to obliteration of marrow spaces and to anemia with myeloid metaplasia and hepatosplenomegaly beginning in infancy, to bone fragility, and to progressive deafness and blindness; autosomal dominant inheritance. There are also autosomal recessive forms, which may be mild [MIM*259710], severe [MIM*259700], or lethal [MIM*259720], and sometimes involve a renal tubular defect [MIM*259730]. A milder, autosomal dominant form has onset in childhood and no neurologic sequelae.

Questions and answers on "Osteopetrosis"

Dear Doctor, I have a patient with infected nonunion fracture shaft femur with osteopetrosis. was operated 4 years back with DCP, got infected...

doctor1 MD

hi,

thank-you for providing the brief history.

As the surgery was failure trying the trying the iliazarov ring fixator should work well but may...

Read Full Thread   Ask a Doctor Now

Hi, I am 49 years of age, 160cm, 73 kg. i have an hereditary bone disease, osteopetrosis which causes me to break bones easily and gives me...

doctor1 MD

Dear,

Thanks for your query.

Established procedure for diabetic retinopathy is to have flourocine angiography followed by laser photocoagulation....

Read Full Thread   Ask a Doctor Now

I am a dangerously obsese (325lbs/5'3"), female with pulmonary hypertension, arthritis, type 2 diabetes,
thyroid problems and very limited...

doctor1 MD

Brief Answer:
Hi

Detailed Answer:
Good dear,

Noted your concerns. Is the bone condition what you are mentioning Osteopetrosis or PAget's disease ?...

Read Full Thread   Ask a Doctor Now

Recent questions on Osteopetrosis


Ask Question
Doctor Image
MD

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

Related Drugs/Medications
Related Treatment/Therapy
Related Medical Topics