Neuromuscular junction diseases
What is Neuromuscular junction diseases?
An example of neuromuscular (NM) junction diseases is Myasthenia gravis. Here antibodies are directed against the acetylcholine receptors at the motor end plate at the NM junction. As a result acetylcholine cannot bind to these receptors to bring about muscle contraction resulting in progressive muscle weakness with activity. Ocular muscle are most commonly affected.
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