Myeloma

What is Myeloma?

Multiple myeloma is cancer that starts in the plasma cells in bone marrow. Bone marrow is the soft, spongy tissue found inside most bones. It helps make blood cells. Plasma cells help your body fight infection by producing proteins called antibodies.

Questions and answers on "Myeloma"

My father has just started to find out that he has multiple myeloma cancer. He had a bone marrow sample taken yesterday to find out the extent, but last night he started passing a lot of blood. My family took him to the hospital and he is in need of blood this morning. Is passing blood a symptom of the multiple myeloma diagnosis? I live out of state and am curious on how serious this is... Any advise? ~son

doctor1 MD

hi.

it is best if you bring your father to the nearest hospital or ER if he is passing out blood. his blood count might be dropping if this happens frequently. also, a consultation with a medical oncologist is best for further evaluation and management of his condition.

hope this helps.

good...

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I am a myeloma patient. Was first diagnosed in 2012. Now i have rib lesion on the ct scan and biopsy shows active plasma but bone marrow is normal. Relapse?

doctor1 MD

No it's not relapse but it's a bone metastasis.

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My new GP has noticed that my white blood cell count has been lower than normal for about three years. previous GPs have never mentioned it.
It coincides with a hip and thigh replacement and I wondered if they could be connected.

doctor1 MD

Brief Answer:
They are not likely connected.What are the numbers? What drugs did you take

Detailed Answer:
Hi and thank you so much for this query.

I am so sorry to hear about this low White blood count that you have reported. It is unlikely that both are related unless you used a drug during...

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I received the following results from a blood test. What do they mean?
lgG 723mg/dl lgM 33 mg/dl Kappa Free Light Chains 51.0 mg/dl
Lambda Free Light Chains 0.6820 mg/dl Kappa/Lambda FLC Ratio 74.8

doctor1 MD

Brief Answer:
You may have kappa chain myeloma.

Detailed Answer:
Hi, dear
I have gone through your question. I can understand your concern.

You have gone through free light chain assay.
Your Ig G and Ig M level is not much high. But your kappa free light chain level is high with high Kappa/lamda...

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I have recently been having hip pain as well as foot pain and knee pain all on same side of body. I went to the doctor and he ran some blood work of which was c reactive protein (normal) and my esr level which was normal as well( 1 to be exact) I was concerned about myeloma or perhaps cancer and autoimmune disorders such as lupus so when the doctor said my esr would likely be high if I had these diseases it put my mind at ease a bit that it was normal . But now I remembered I forgot to tell him that I think I took some naproxens for a few days before the test. Now im thinking the naproxens affected my results and im anxious all over again. Do you think naproxen would affect my levels that much as to affect a true reading.

doctor1 MD

Brief Answer:
NO!

Detailed Answer:
Hi and thank you so much for this query.

I am so sorry to hear about pain and all the inconvenience that this has caused you. An ESR of 1 cannot be explained by taking naproxene. Even if it were high and you are taking the most potent drugs for the condition, it...

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Ok so we went to Mayo to see about the graduating pain along the mid- spine. I though the myeloma was gone.
1. Hypermetabolic lymph nodes involving the right neck, right external iliac
chain and bilateral inguinal regions suspicious for extraskeletal myelomatous
involvement. Another consideration is reactive change. Clinical correlation is
recommended. Tissue sample diagnosis is suggested if clinically indicated.
2. No lytic lesion involving the bony structures.
please review the former reports and compare them to the current info sent

doctor1 MD

Brief Answer:
Hello. you require regular follow up

Detailed Answer:
hello again. so you had smoldering myeloma and that was confirmed by your physician too. Now the pentct is showing up few nodes but these are likely to be reactive/infectious in nature rather than myeloma as myeloma is unlikely...

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My mother has stage 3 Multiple Myeloma (61 yo, Caucasian, 5'6", 103#). Dx'd 15 mos ago after bout w/ pneumonia. Failed on Velcade, Failed on Revlimid. Now on Krypolis, but M-spike is still 5. Last GFR was 51% Needs blood transfusions often (4-7 units monthly) , pain is high (just finished palliative radiation to pelvis for pain mngmnt and hoping to steady her gait. Question- I'm having a hard time finding life expectancy info. This will impact decisions (should I go on FMLA now? etc) I understand that it varies and cannot be predicted down to the exact day, but some sort of time frame would be helpful. She is wasting away and in pain, its difficult to watch her suffer. I would like a XXXXXXX answer, her oncologist is sweet and keeps her hopeful, so I have not been able to inquire further with him.

doctor1 MD

Brief Answer:
median survival is between 23 to 29 months

Detailed Answer:
Hello XXXXXXX

Sorry about your mom; I have read your query in detail.

According to Salmon-Durie staging system for MM, the median survival of Stage III patients is 23 months.

According to The International Staging System of...

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Doctors do not know what is causing my uveitis. Could stress be causing it?

Medications tried. Not concept, I meant cellcept.

Also being monitered for Myeloma.

doctor1 MD

Brief Answer:
Are you able to close your eyes well?

Detailed Answer:
Hi and thanks for this query.

Am curious and would like to know if you are able to close the eyes well? Did this start after the extensive surgery on the neck region or before? This is because the nerve which controls the...

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I just realized I am having trouble walking, losing my balance, having leg and hair tremors as well as making new facial expressions. I am a 70 year old female with primary amyloidosis and smoldering myeloma and have not had chemo. I am thinking I also have Parkinson's disease. Quite the trifecta. Husband, brother, father all physicians and helpless. Thanks.

doctor1 MD

Brief Answer:
You should get MRI of the brain

Detailed Answer:
Hello mam,
I have studied your case and I understand that you are having tremors and difficulty in walking . These symptoms suggest that there is some patholgy in your brain. I have following possibilities in my mind.
1. Myeloma...

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Hi,

My mother is diagnosed with Multiple Myeloma. The plasma cell count was 15% and we underwent 4 cycles of chemo

My current oncologist is suggesting 3 more cycles of chemo. As the biopsy results shows 7% plasma cells. Do we need chemo or can we sustain on medication without chemo as we are under 10%

doctor1 MD

Brief Answer:
depends on transplant or no transplant

Detailed Answer:
Hi
Thanks for following up.

Considering that she has a partial response now, she can go directly for the autologous transplant. Because if we are planning transplant then 4-6 cycles is the ideal time.

But if the doctors feel...

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Recent questions on  Myeloma

doctor1 MD

Ok so we went to Mayo to see about the graduating pain along the mid- spine. I though the myeloma was gone. 1. Hypermetabolic lymph nodes involving the right neck, right external iliac chain and bilateral inguinal regions suspicious for...

doctor1 MD

I have been diagnosed with Chrones IBD and FIbromyalgia however in a routine blood test they found my Serum Light bloods high ie 34 compared to normal -20. Urine was normal kidneys creatin up ..other kidney tests normal except for a complex cysts...

doctor1 MD

Hello, I recently had flow cytometry test done on Peripheral blood. Reason for the test was mildly elevated relative lymphocyte count . The Absolute count was fine. Below is the report of the Flow cytometry. I would like to have it reviewed by a...

doctor1 MD

My father has just started to find out that he has multiple myeloma cancer. He had a bone marrow sample taken yesterday to find out the extent, but last night he started passing a lot of blood. My family took him to the hospital and he is in need of blood this morning. Is passing blood a symptom of the multiple myeloma diagnosis? I live out of state and am curious on how serious this is... Any advise? ~son

doctor1 MD

my father has multiple myeloma cancer and is on his 2nd chemo cycle before a donor transplant and has decided to quit cold turkey, the transplant is a haploid and he has already had this for now 3 years, undergoing 2 previous auto stem cell transplants, will discontinuing chemo make him ineligible to do the haploid transplant? His cancer has been extremly aggressive on his back bones and hips. Any advise about his current decision?

doctor1 MD

hello there. I had a severe burning sensation underneath my breasts, up my esophagus across my jaw. The pain in my rids was very severe and the pressure made my throw up a little. The pressure would not let up and the pain was awful. My husband called 911 and the doctor there could not find anything in my blood of heart ultrasound. They gave me some zantac and some antacid and morphing for the pain. I went home and I felt better but I still have a dull pain in my chest, but I do feel a lot better. I have been reading that I probably just had a bad acid reflux attack. I hope it was that rather than a heart attack. Could I get your opinion please and thank you.

doctor1 MD

Hi, i am a myeloma survivor, i am having right lower rib pain. It is getting better if i wear belt supporting dorsal spine. Also when i rest and sleep. When i stand for longer period it gets worst. I was operated on d8 d9 for cord compression due to tumor 3 years back. Under went 7 cycles of len dex therapy than had autologus bone marrow transplant. Now in complete i dont know what causes this pain.?.

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