Immune thrombocytopenia

What is Immune thrombocytopenia?

Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenia, primary immune thrombocytopenia, primary immune thrombocytopenic purpura or autoimmune thrombocytopenic purpura, is defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia. It causes a characteristic purpuric rash and an increased tendency to bleed. Two distinct clinical syndromes manifest as an acute condition in children and a chronic condition in adults. The acute form often follows an infection and has a spontaneous resolution within 2 months. Chronic idiopathic thrombocytopenic purpura persists longer than 6 months with a specific cause being unknown.

ITP is an autoimmune condition with antibodies detectable against several platelet surface antigens.

ITP is diagnosed by a low platelet count in a complete blood count (a common blood test). However, since the diagnosis depends on the exclusion of other causes of a low platelet count, additional investigations (such as a bone marrow biopsy) may be necessary in some cases.

In mild cases, only careful observation may be required but very low counts or significant bleeding may prompt treatment with corticosteroids, intravenous immunoglobulin, anti-D immunoglobulin, or immunosuppressive drugs. Refractory ITP (not responsive to conventional treatment) may require splenectomy, the surgical removal of the spleen. Platelet transfusions may be used in severe bleeding together with a very low count. Sometimes the body may compensate by making abnormally large platelets.

Questions and answers on "Immune thrombocytopenia"

Hello, I am a 34 years old woman, and I am very afraid I may have a serious health problem.

For the last 9 months, I got regular platelet count by...

doctor1 MD

Brief Answer:
Hello dear. No need to afraid

Detailed Answer:
Hello dear. I have gone through the details. Your reports seem to be ok. The platelet...

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well im 20 and have a disease thats called immune thrombocytopenia ... my problem is that when i drink milk i get loose motions.. it causes a...

doctor1 MD

hi i had gone through your query and understand your concerns. i would come up with the possibility of MILK ALLERGY (intolerance of milk ) is the...

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When my daughter was born it was discovered she had isoimune thrombocytopenia. My daughter just advised me she is 16 weeks along and wants to tell...

doctor1 MD

Brief Answer:
She need to be tested for the "antiD"& Rh

Detailed Answer:
Hi,

I am dr XXXXXXX and I will try my level best to address your concerns....

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Recent questions on  Immune thrombocytopenia

doctor1 MD

Dear Doctor, I've arranged my CBC test results since 2008 in an excel for easy analysis. Sir could you please adivse if this could be ITP or...

doctor1 MD

My father in law is admitted to hospital. His peletlet level is going down every four days and he is having problem in lungs. Biopsy is negative,...

doctor1 MD

What causes low blood platlets?

doctor1 MD

well im 20 and have a disease thats called immune thrombocytopenia ... my problem is that when i drink milk i get loose motions.. it causes a...

doctor1 MD

hey my sister had 3 miscarraige..and her blood platlets count very low.its 50 k only... after all check up ,her spleen came large... i wanted to...

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