Hyperkeratosis

What is Hyperkeratosis?

Hyperkeratosis (from Ancient Greek: ὑπέρ (hyper, “over”); keratos - keratin) is thickening of the stratum corneum (the outermost layer of the epidermis), often associated with the presence of an abnormal quantity of keratin, and also usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed to assess minor degrees of hyperkeratosis.

It can be caused by vitamin A deficiency or chronic exposure to arsenic.

Hyperkeratosis can also be caused by B-Raf inhibitor drugs such as Zelboraf.

It can be treated with urea-containing creams, which dissolve the intercellular matrix of the cells of the stratum corneum, promoting desquamation of scaly skin, eventually resulting in softening of hyperkeratotic areas.

Questions and answers on "Hyperkeratosis"

Can you tell me what corresponds this little white task on my tongue. It is flexible and not painful. I'm worried ?

doctor1 MD

Brief Answer:
Hyperkeratosis of the tongue

Detailed Answer:
Hi

Thanks for posting the query

I have examined the picture thoroughly and I am of the...

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Skin on palms turned thick, white, wrinkled and bumpy in shower. Mild pain and scratchy sensation (no itch). Most symptoms disappeared when dry but...

doctor1 MD

Brief Answer:
Hyperkeratosis of palms

Detailed Answer:
Hello
Thanks for the query and photograph.
You have developed hyperkeratosis of palms.
It...

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Hello I have a supple white lesion for 3 weeks which regresses and returns. It seems to be placed next to a somewhat prominent tooth. Do you think...

doctor1 MD

Brief Answer:
Please upload a picture..

Detailed Answer:
Hi..
Thanks for the query..

First of all I would like to tell you that if the lesion...

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Recent questions on  Hyperkeratosis

doctor1 MD

Hi, I have a small tiny black dot in left inner cheek. I have this new thing I just found. It honestly looks like someone took a black pen and made...

doctor1 MD

Good morning - My Wife has had a scab on her nose that heals and then re-scabs and then heals and re-scabs for about 3-4 weeks. The wound area is...

doctor1 MD

My hand are very dry. there are demarcation dark colored. Sometime itchy but, not often.

doctor1 MD

i am taking treatment from aiims ,but doctor was not there to chek my report,and now i am givinng you my skin report so please tell me about my...

doctor1 MD

I have got lesions of localised hyperkeratosis on both soles of feet. Both feet are dry and with cracks.Some doctor has pescribed application of...

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