What is Histoplasmosis?

Histoplasmosis Cave disease or Darling's disease or Reticuloendotheliosis is a disease caused by the fungus Histoplasma capsulatum. Histoplasmosis is common among AIDS patients because of their suppressed immunity. In immunocompetent individuals, past infection results in partial protection against ill effects if reinfected.

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Questions and answers on "Histoplasmosis"

Hi. I had a chest xray while in the hospital for some back of head headache issues. The xray came back "hyperaerated lungs with mild increased interstitial markings." I never did find out reason for headaches. Then two weeks later an unenhanced CT scan was done. Here are the findings: "No evidence of pulmonary nodule, infiltrate or consolidation. There is no evidence of mediastinal adenopathy or pulmonary mass. Focal calcified mediastinal lymph nodes." So I am worried about the last part of that! I understand calcified can mean old infection but I looked up the various causes, like TB or sarcoidosis and fungal infections or histoplasmosis and never had any of those! WHat does "Focal" mean also? And, what about the interstital markings on the chest X-ray? Would they have shown up on the CT scan wondering why they were not addressed. For reference I am 45 yrs old nonsmoker (but grew up on in a smoking house). I am very athletic and do not seem to have any breathing problems. Please advise.
Brief Answer:
Yes, it may indicate infection or sarcoidosis.

Detailed Answer:
Hello Dear,

Thanks for posting your query on XXXXXXX

The findings mentioned in the chest x ray are not present in the CT chest. But the findings mentioned in the CT chest do not give a clear picture and are a little...
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Dear Sir, I went for Saudi Visa medical test, initially they took X-ray and said there is an issue, so advised to take CT scan for further investigation. The observation is as follows. I have been selected as Electronic Engineer, which is mostly inside control room with no field work. Kindly inform if the following is to be worried. 1. parenchymal scar noted in left lingula 2. Tiny calcific foci noted in right lower paratracheal lymph nodes 3. Tiny parenchymal scar noted in the middle segment of right middle lobe
Brief Answer:
Need further investigations.Sputum, Scopy, Culture

Detailed Answer:

Thanks for your query.
I have gone through your query and understand your concern.

It is very difficult to interpret with just CT scan findings.
Because Parenchymal scars in lung and calcium deposits in para...
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Re histoplasmosis in a friend. They haven't found something he responds to . Now has 37% lung function, on o2 24/7. last ditch the natl jewish doctor put him on prednisone. Where it helps with the breathing in the short run, would his immune system be further compromised?

It seems your friend has developed pulmonary histoplasmosis. Treatment differs according to chronicity of the disease :
If it is acute ( recent onset ), an antifungal therapy either with itraconazole or amphotericin B. Alongwith it, prednisone therapy is needed for initial 1-2 weeks

If it...
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I have been experiencing pressure pain in my heart area, exhaustion, shortness of breath, constant pressure in chest which worsens with exertion, worsening anemia and just haven t felt well. Cardiologist nuclear test revealed heart is in great shape. I work out constantly and live a healthy lifestyle. My CT scan revealed 5.4mm calcified granuloma in right upper lob and 5mm granuloma in left upper lob, multiple calcified hilar and mediastinal lymph nodes. What does this mean?
granuloma is a small area of inflammation in tissue. Granulomas are most often the result of an infection and most frequently occur in the lungs.over time, granulomas become calcified and have the same density as bone,
Infections that are characterized by granulomas include tuberculosis, leprosy,...
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I had a little puss on the back of my throat about three weeks ago and it was diagnosed as tonsillitis and a round of amoxic. was prescribed. My tonsils never got swollen or got worse. I had a tight feeling at the bottom of my throat that got worse and moved up; I now have a pus or yellow/white coating on the back of my tongue , swollen lymph nodes in neck and chest, the feeling of something in my lower throat and like i need to burp. I got a shot of penicillin 2 weeks ago and nothing got better. I'm on a zpack not and it is not helping. what if anything could I do and what the heck is this??

Thank you
Brief Answer:
Complete Peni V regimen, 10days and throat swab

Detailed Answer:
Hi and thanks for the query,

I understand it can be disturbing taking drugs without any improvement. However, I think the option of the penicillin as choice of drug was reasonable. However, persistence of symptoms...
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I was recently given a CT scan following a chest xray that showed calcified granulomas. The results show:
Left lower lobe calcified granulomas with left hilar and mediastinal calcified lymph nodes with no pleural effusion.
I also have been having shortness of breath occasionally (more often at night) for the last ten months, although it has been getting better. They started last XXXXXXX following a long period of travel to XXXXXXX I have started having knee pain in both knees which I have never had before, and also have numbness in my ring and pinky finger on one hand (for about the last three months).
I traveled to XXXXXXX CA for 8 years working in the oil fields and am now wondering if these could all be related symptoms of valley fever.
Brief Answer:
Symptoms suggestive of histoplamosis or sarcoidosis, further inv required

Detailed Answer:
Thanks for posting your query on HealthcareMagic.
Valley fever can be a possibility since you have recently been to California where the disease is endemic.Shortness of breath and knee...
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I was diagnosed with Polymyalgia Rheumatica in XXXXXXX 2012. I have been on 5-10mg of Prednisone for the past 2 years. This Feb I got whatever was going around that was termed as Bacterial/Viral with the bad cough. I recovered with antibiotics. I did have a break through PMR pain. When I was diagnosed I had a slightly elevated ESR and C reactive Protein. Over the past 2 months my ESR is 92 (<30) my C reactive Protein is 1.7 <.80 and white blood 18.8 Thousand/ul 3.8-10.8 MCH 26.7 (27-33) RDW 15.2% low vit D and B12. I had possible symptoms of GSA, and will have a biopsy next week. I have been on 40mg of Prednisone for a week. IF GSA is negative what are other possibilities, and is it worth further investigation. Oh, and I have a history of Histoplasmosis, which was treated with antifungal, but left necrotic lung tissue. I am a 53 year old female.
Brief Answer:
Lot more differential diagnosis are there.

Detailed Answer:

I have gone though your query.

Tests for polymyalgia rheumatica has already done in your case, there are no other useful tests which can be done. I think you have mistakenly written GSA in place of G.C.A which is giant cell arteritis...
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I am 63 and have Dercums Disease, Polycythemia Vera, Aspergillus Fumigatus, Hereditary Angioedema, leaking heart valve, RLS, COPD, Diebetes, Emphysema and have had Histoplasmosis twice. Can some of these be related? Thank you, Barbara Seymour YYYY@YYYY
1. Dercum disease can be present in a person with polycythemia vera, the exact cause is unknown but this can be caused by the fat cell dysfunction, mechanical pressure on the nerves.

PS: the disease is chronic and progressive, thusprognosis depends on the medical conditions present or...
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Had a lung ct. noted more prominent soft tissue density to the right middle lobe bronchi,also an adjacent punctuate calcification
Brief Answer:
Please re-upload the reports.

Detailed Answer:
Hello SueandDickMerkner
Thanks for writing to us

Lung mass with adjacent calcification may be due to many reasons.
Sorry,i am unable to see your attached reports/images.
Please upload it again so that i can interpret the findings.

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