Hereditary nonpolyposis colorectal cancer

What is Hereditary nonpolyposis colorectal cancer?

An autosomal dominant predisposition to early-onset colorectal cancer in the absence of adenomatosis. The disease phenotype may be limited to the colorectum (Lynch syndrome I) or coexist with extracolonic tumors such as endometrial or gastric cancer among others (Lynch syndrome II). The genetic basis is in one of several genes responsible for DNA mismatch repair; in over 90% of cases, the mutation is one of two genes: MSH2 and MLH1.

Questions and answers on "Hereditary nonpolyposis colorectal cancer"

I am 45 years old and in 2008 I had my gall bladder removed.2 years ago I hade a benign polyp removed.

My father passed away with bowel cancer as...

doctor1 MD

Brief Answer:
you are free of trouble but on the radar

Detailed Answer:
Thank you for asking

Lynch syndrome is Hereditary non polyposis colorectal...

Read Full Thread   Ask a Doctor Now

Hello... I tend to have a lot of health anxiety and am very conscious about racking my skin. I see the dertmatologist for yearly skin cancer...

doctor1 MD

Brief Answer:
Everything is normal, no need to worry

Detailed Answer:
Hi
Thanks for being at HealthcareMagic
I have gone through your complaints as...

Read Full Thread   Ask a Doctor Now

Hi,

I am a 23 year old female and I have been noticing bright red blood in my solid stools for the last couple of weeks. My maternal grandmother...

doctor1 MD

Hello!

Thank you for the query.

Bright red blood in the stool is usually caused by hemorrhoids. Especially if the blood is on the surface of the...

Read Full Thread   Ask a Doctor Now

Recent questions on  Hereditary nonpolyposis colorectal cancer

doctor1 MD

Hello... I tend to have a lot of health anxiety and am very conscious about racking my skin. I see the dertmatologist for yearly skin cancer...

doctor1 MD

I am wondering about Gilbert's syndrome and related cancers? My older brother has pancrititis and my mother is in her final stages of pancriatic...

doctor1 MD

I'm worried i have hnpcc. grandmother: colon cancer age 66 (survived, died of heart disease age 76), father: adenomatous polyp(s) age 46, now age...

doctor1 MD

I am a 17 year old girl. It has been 3 months that i have skipped my period. I first got my period when I was 16. I have experienced more than...

doctor1 MD

Is it true that if I have my gall bladder removed I am at a higher risk for cancer...I am Lynch Syndrome positive and my mom died of colon...

doctor1 MD

I am 45 years old and in 2008 I had my gall bladder removed.2 years ago I hade a benign polyp removed. My father passed away with bowel cancer as...

doctor1 MD

Hi, I am a 23 year old female and I have been noticing bright red blood in my solid stools for the last couple of weeks. My maternal grandmother...

Ask Question
Doctor Image
MD

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

Related Drugs/Medications
Related Procedures
Related Medical Topics