Hereditary nonpolyposis colorectal cancer

What is Hereditary nonpolyposis colorectal cancer?

An autosomal dominant predisposition to early-onset colorectal cancer in the absence of adenomatosis. The disease phenotype may be limited to the colorectum (Lynch syndrome I) or coexist with extracolonic tumors such as endometrial or gastric cancer among others (Lynch syndrome II). The genetic basis is in one of several genes responsible for DNA mismatch repair; in over 90% of cases, the mutation is one of two genes: MSH2 and MLH1.

Questions and answers on "Hereditary nonpolyposis colorectal cancer"

I am 45 years old and in 2008 I had my gall bladder removed.2 years ago I hade a benign polyp removed.

My father passed away with bowel cancer as...

doctor1 MD

Brief Answer:
you are free of trouble but on the radar

Detailed Answer:
Thank you for asking

Lynch syndrome is Hereditary non polyposis colorectal...

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Hello... I tend to have a lot of health anxiety and am very conscious about racking my skin. I see the dertmatologist for yearly skin cancer...

doctor1 MD

Brief Answer:
Everything is normal, no need to worry

Detailed Answer:
Thanks for being at HealthcareMagic
I have gone through your complaints as...

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I am a 23 year old female and I have been noticing bright red blood in my solid stools for the last couple of weeks. My maternal grandmother...

doctor1 MD


Thank you for the query.

Bright red blood in the stool is usually caused by hemorrhoids. Especially if the blood is on the surface of the...

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