Erythroblastosis fetalis

What is Erythroblastosis fetalis?

Hemolytic disease of the newborn, also known as hemolytic disease of the fetus and newborn, HDN, HDFN, or erythroblastosis fetalis, is an alloimmune condition that develops in a fetus, when the IgG molecules (one of the five main types of antibodies) produced by the mother pass through the placenta. Among these antibodies are some which attack the red blood cells in the fetal circulation; the red blood cells are broken down and the fetus can develop reticulocytosis and anemia. This fetal disease ranges from mild to very severe, and fetal death from heart failure (hydrops fetalis) can occur. When the disease is moderate or severe, many erythroblasts are present in the fetal blood and so these forms of the disease can be called erythroblastosis fetalis (or erythroblastosis foetalis).

Questions and answers on "Erythroblastosis fetalis"

Prior to the development of Rhogam , a woman with blood type O- giving birth to a baby with blood type A+ had a 2% chance of developing an immune...

doctor1 MD

Hi,
Previously it was seen and thought that ABO incompatibility protects against pregnancy induced Rh hincompatibility.But there were some reports...

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Prior to the development of Rhogam, a woman with blood type O- giving birth to a baby with blood type A+ had a 2% chance of developing an immune...

doctor1 MD

Hello,
Thanks for posting your query.
The risk depends on the chances of feto maternal hemorrhage prior to the birth of the baby. The chances of...

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Hi, I recently learned my Father was Rh Positive and my Mother is Rh Negative . I was born in 1957 - the second of six children. I know sometime in...

doctor1 MD

Hello Clara,

Thanks for posting,

If you and your siblings did not develop any complications at birth due to mother and fetus incompatibility then...

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Recent questions on  Erythroblastosis fetalis

doctor1 MD

i have undergone an abortion since July 11 2013 and i didn't take the anti d shot. my blood type is O Negative and since then i have been trying to...

doctor1 MD

Hi, I recently learned my Father was Rh Positive and my Mother is Rh Negative . I was born in 1957 - the second of six children. I know sometime in...

doctor1 MD

Prior to the development of Rhogam , a woman with blood type O- giving birth to a baby with blood type A+ had a 2% chance of developing an immune...

doctor1 MD

Hi Doctor, My wife is 17 weeks pregnant. We did an electrophoresis test ( report attached ), and found that she is thallesemia minor. What should...

doctor1 MD

Prior to the development of Rhogam , a woman with blood type O- giving birth to a baby with blood type A+ had a 2% chance of developing an immune...

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