What is Desmoid?

Aggressive fibromatosis is a rare condition marked by the presence of desmoid tumors, which are benign, slow-growing musculoaponeurotic tumors without any metastatic potential. However, aggressive fibromatosis is locally aggressive. Despite their benign nature, they can damage nearby structures causing organ dysfunction. Most cases are sporadic, but some are associated with familial adenomatous polyposis (FAP). Approximately 10% of individuals with Gardner's syndrome, a type of FAP with extracolonic features, have desmoid tumors.

Histologically they resemble low-grade fibrosarcomas, but they are very locally aggressive and tend to recur even after complete resection. There is a tendency for recurrence in the setting of prior surgery; in one study, two-thirds of patients with desmoid tumors had a history of prior abdominal surgery.

Risk factors for desmoid disease amongst FAP patients include female sex, a 3' APC mutation, a positive family history and a history of previous abdominal surgery.

Questions and answers on "Desmoid"

Child my neice had a neurofibroma at left ankle,now she has been diagnosed with desmoid type fibromatosis at the same joint. Kindly me know the...

doctor1 MD

Brief Answer:
They are not related to each other.

Detailed Answer:
Neurofibroma and Desmoid type Fibromatosis are different conditions....

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I'm a 47 yr old male, married with 5 kids and living in the rep of Ireland , I've been very sick all my life and doctors all over Ireland...

doctor1 MD

Thank for asking to HCM
You have gone through the numbers of surgeries, you have multiple pathologies
and still it is continue to happened, you...

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I have a constant tender pain about 1-2 inches above the navel that is XXXXXXX (coming from a pinpoint location). It feels like I've been punched...

doctor1 MD


Thanks for the query.

Pain in the supraumbilical region is usuallt foregut in origin. The organs arising from the foregut are the esophagus,...

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