Demyelinating disease

What is Demyelinating disease?

Generic term for a group of diseases, of unknown cause, in which there is extensive loss of the myelin in the central nervous system, as in multiple sclerosis and Schilder disease.

Questions and answers on "Demyelinating disease"

57 yr old brain mri impression, focal areas of increased flair and t2 signal are noted in the left periventricular white matter adjacent to the frontal horn of the lateral ventricle as well as in the deeper periventricular white matter in the left frontal lobe area. these could be due to microvascular ischemic disease, although a demyelinating disease is also possible. note that no abnormal enhancement is noted at these locations. what does this mean.

doctor1 MD

Welcome to Health care magic.

1.Microvascular ischemic changes are age related changes seen in elderly age.
2.It happens - over some age the small vessels gets thickened and closed and seen on MRI as focal areas / or areas or brain without blood supply.
3.Similar changes are seen in the...

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I was diagnosed with demyelinating disease in November 2008 but in October the same year I treated carpets & bedding with a household flea treatment after my cats had fleas. I tried not to inhale but I could smell and taste it even though I covered my mouth and nose. Could this be a cause of my condition?

doctor1 MD

Hi thanks for asking question in HCM.
In the demyelinating disease,myeline sheath got damaged.
It could be because of congenital genetic cause, trauma or inflammation or infection of brain or spinal cord.
During house flea treatment mere inhalation will not lead to demyleniting disease.So it...

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I had a MRI recently and these were the findings...my Dr. says everything was normal.
"Two small hyperintense FLAIR foci in the right frontal lobe
subcortical white matter are nonspecific and do not meet MR criteria
for demyelinating disease." If it was normal...why are my headaches so severe, why
are my legs and feet numb and why is my memory so terrible? I have 4 family members with
MS....

doctor1 MD

Hi,

Though MRI brain does not meet criteria for demyelinating disease, but MRI brain is not normal, it has two small hyperintensity in R) frontal lobe which can produce pain and weakness in left half especially L) lower limb(leg), these area also precipitate seizure hence episodic headache can be...

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We had contact before about the brain MRI. I have done a new brain MRI with contrast and the report says: There are areas of decreased signal that do resemble black holes and may be consistent with the diagnose of demyelinating disease.

It is more on the right side, could this be the reason that my pain is mostly on my left body side?

Thank you very much

doctor1 MD

Hi,

Thank you for getting back.

You are correct. Right side of brain sends nerve impulses to the left side of body. So, your left sided symptoms are related to the lesions on the right side. So, your pain is most likely related to them.

Best wishes,
Dr Sudhir Kumar MD DM (Neurology) XXXXXXX...

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My wife has done MRI today and the below mentioned Impression was revealed two tiny hyperintense foci in the bilateral frontal subcortical white matter without mass effect. Possibility of ischemic lesions versus demyelinating disease (unlikely) needs to be considered. clinical correlation and imaging follow up suggested. what does they mean and what is remedy for that

doctor1 MD

Dear friend, welcome and thanks for entrusting your query here at Healthcaremagic!
I am Dr. Prasad Akole (Critical Care Expert- http://bit.ly/Dr-Prasad-Akole) and am glad to address to your query here.

The MRI brain shows two small spots in the deep forebrain which turn bright on the scan and not...

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i recently had an mri of my brain and it showed 4 lesions wich was diagnosed as ms/ at the same time i am seeing a urologist for bladder problems and he seems to think it related. now i had the evoked potential done and they were within normal limits/ also on my mri i said i had empty sella syndrome, and that when it presses on my pituitary ( wich is flat as a pancake) i get a horrible headache and fluid starts dripping from my nose. now both mu neurologist and my pcp dont seem to be concerned but i looks it up at johns hopkins and its a rare desease, could this be contributing to the ms symptoms

doctor1 MD

Hello and welcome to HCM,

Multiple sclerosis (MS) is a demyelinating disease usually picked up on the MRI.
Urinary bladder involvement is common in MS due to demyelination of the spinal nerves.
Headache and dripping of fluid from nose suggests CSF rhinorrhea.
In this case CSF (fluid which is...

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Recent questions on  Demyelinating disease

doctor1 MD

I had an MRI W/o contrast three years ago and it foundscattered white matter flairhyperintensities indicating a demyelinating processes such as inflammatory, infectious and vascultic- just had mri w and w/o contrast found multiple nodules of...

doctor1 MD

Since more than 10 years, I ve been suffering from memory loss and the only thing I love in this life is math. but suddenly I don t do well in it anymore and here where i started to panic. I did x-ray to get have nasal septum deviation surgery. then i was asked to do MRI. My MRI report findings: Subtle right frontal subcortical white matter focus of signal alteration,this finding is not specific it might represent changes associated with migraine less likely vasculitis or demyelinating disease? what do you think?

doctor1 MD

A 25-year-old woman is admitted to the hospital after suffering a seizure . She has not had a personal history of seizures in the past. On admission, an MRI scan demonstrates that the patient has multiple sclerosis . When the nurse initially meets...

doctor1 MD

Brain MRI indicated: multiple scattered nonspecific foci of increased-T2 signal involving the perventricular and subcortical white matter bilaterially. It also said differential includes the sequela of chronic microvascular ischemic changes,...

doctor1 MD

I was diagnosed with demyelinating disease in November 2008 but in October the same year I treated carpets & bedding with a household flea treatment after my cats had fleas. I tried not to inhale but I could smell and taste it even though I covered my mouth and nose. Could this be a cause of my condition?

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