Chronic granulomatous disease

What is Chronic granulomatous disease?

A congenital defect in the killing of phagocytosed bacteria by polymorphonuclear leukocytes, which cannot increase their oxygen metabolism due to dysfunctional NADPH oxidase, either because of defective cytochrome [MIM*233710 and MIM*233690] or other specific factor deficiencies [MIM*233700 and MIM*306400]. As a result there is an increased susceptibility to severe infection by catalase-positive microorganisms; inheritance is usually autosomal recessive or X-linked.

Questions and answers on "Chronic granulomatous disease"

My cousin sister had a son 2 yrs old who was diagnosed to have chronic granulomatous disease expired 2 months before .., now she is 4 months...

doctor1 MD

hI. sINCE SHE is already 4 months pregnant, you have missed 1st trimester tests like, NT Scan, blood tests. But now she should have level 2 scan to...

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I had a ct chest w/o contrast I've had trouble with my lungs for years it said a few things but I wanted to know about this part Calcified...

doctor1 MD

welcome to Health care magic.

Calcified granulomas are seen after a healed infection, same thing with the calcified lymph nodes in the hilar region...

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My 2 year old daughter suffers from recurrent high fevers (103-104). She has been hospitalized twice for pyelonephritis and went septic with it at...

doctor1 MD

Brief Answer:
Immunodeficiency needs to be ruled out

Detailed Answer:
Hi...I have a few questions for you.

1. What was her birth weight and current...

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