What is Cardiac amyloidosis?
Cardiac amyloidosis is any of several forms of amyloidosis (the accumulation of inappropriately folded proteins) in or affecting the heart.
Amyloid deposition in the heart can cause both diastolic and systolic heart failure. EKG changes may be present, showing low voltage and conduction abnormalities like atrioventricular block or sinus node dysfunction. On echocardiography the heart shows restrictive filling pattern, with normal to mildly reduced systolic function. The most common form of amyloidoses, AA amyloidosis, usually spares the heart.