What is Adrenoleukodystrophy?

An X-linked recessive disorder affecting male children, resulting from a defect in long-chain fatty acid metabolism and characterized by chronic adrenocortical insufficiency, skin hyperpigmentation, progressive dementia, spastic paralysis, and other intellectual and neurologic disturbances; results from myelin degeneration in the white matter of the brain. The causative gene maps to Xq and encodes adrenoleukodystrophy protein (ALDP), an ATP-binding transporter located in the peroxisomal membrane. A mild form of ALD affecting older male children, as well as adolescent or adult males is called adrenomyeloneuropathy

Questions and answers on "Adrenoleukodystrophy"

Hi there! I'm doing a report for my biology class, and I could not find the answer to my question anywhere. I thought that you might be able to...

doctor1 MD

Thanks for writing in.

There is a lot of variability between the age of onset of problems, the rate of the disease progression, and the life...

Read Full Thread   Ask a Doctor Now

Hi, is there a treatment for Adrenoleukodystrophy in homeopathy?

doctor1 MD

Brief Answer:
Management and Treatment Aspect

Detailed Answer:

Thanks for raising your concern and the recommended guidelines for his age...

Read Full Thread   Ask a Doctor Now

Was wondering if Lorenzo s oil can help people with MS. My brother-in-law has MS. He is about 49 years old and we are worried about him. He has a...

doctor1 MD

Hi, thanks for writing to HCM.

The therapeutic effects of Lorenzo's oil has been studied only in certain rare genetic disorders like...

Read Full Thread   Ask a Doctor Now

Recent questions on Adrenoleukodystrophy

Ask Question
Doctor Image

Hi, I am Dr. Andrew Rynne (Family Physician). I will be guiding you through the process. Please write your question below.

Related Drugs/Medications
Related Treatment/Therapy
Related Medical Topics